Lymph Node Metastasis and Survival in T1b Esophageal Adenocarcinoma Patients

Notable risk factors for lymph node metastasis in T1b esophageal adenocarcinoma include tumor size ≥20mm and poor differentiation. Endoscopic therapy (ET) showed comparable cancer-specific survival outcomes to surgery for selected cases. Age ≥65 years, ET, and chemoradiation therapy were associated with poorer overall survival. However, further large-scale studies are needed to confirm the lack of survival benefit with chemoradiation therapy for these patients.