Notable risk factors for lymph node metastasis in T1b esophageal adenocarcinoma include tumor size ≥20mm and poor differentiation. Endoscopic therapy (ET) showed comparable cancer-specific survival outcomes to surgery for selected cases. Age ≥65 years, ET, and chemoradiation therapy were associated with poorer overall survival. However, further large-scale studies are needed to confirm the lack of survival benefit with chemoradiation therapy for these patients.
Journal Article by Mohapatra S, Ghamdi SSA (…) Ngamruengphong S et 3 al. in Gastrointest Endosc
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