Metabolic and Bariatric Surgery · 1 September 2025

Bariatric surgery significantly improves nonalcoholic fatty liver disease outcomes

One year post-bariatric surgery, 80% of patients showed a notable improvement in the nonalcoholic fatty liver disease (NAFLD) activity score. Nonalcoholic steatohepatitis (NASH) improved in 42.1% without worsening fibrosis, and 78.8% experienced fibrosis improvement. MRI-proton density fat fraction (MRI-PDFF) reliably detected liver fat remission in 72.2% to 90.4% of patients, while a significant decline in MRI-PDFF readings differentiated NAFLD improvement outcomes. These findings clarify surgical benefits for obesity-related liver disease.

Journal Article by Li M, Zeng N (…) Zhang Z et 17 al. in Int J Surg

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