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Upper Gastrointestinal Tract ·

Esophagectomy after chemoradiation boosts survival in non-responders.

Patients undergoing esophagectomy after chemoradiation had more than double the progression-free survival (PFS) and overall survival (OS) compared to non-surgical non-responders (PFS HR: 2.89, OS HR: 2.97).

  • Non-responders receiving surgery achieved OS rates similar to complete responders not undergoing surgery (HR: 1.12).

Surgical intervention is a critical salvage strategy for patients with locally advanced esophageal cancer who exhibit incomplete response to chemoradiation.

Comparative Study by Toapichattrakul P, Santasup K (…) Chakrabandhu S et 5 al. in BMC Surg

© 2025. The Author(s).

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