Rising Rates of Gastric Neuroendocrine Tumors Change Surgical Care

Gastric neuroendocrine neoplasms are on the rise, necessitating improved prognostic tools for better surgical outcomes.

• Incidence increased 16-fold over 46 years, from 0.435 to 7.033 per 1,000,000 people.
• A newly developed nomogram showed superior predictive accuracy (c-index of 0.86) compared to the AJCC staging system.

Understanding these risk factors—age, sex, tumor characteristics, and surgical intervention—can significantly enhance patient selection and outcomes.

• Chemotherapy notably improved survival in high-risk patients identified by the nomogram.