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Upper Gastrointestinal Tract ·

Predictive factors for success in gastric cancer surgery

Gastric cancer patients with peritoneal metastasis can achieve better outcomes through informed conversion therapy decisions.

  • Study found a 19.4% rate of R0 resection in patients who underwent conversion therapy.
  • Patients receiving conversion surgery had significantly longer median overall survival (p<0.001).
  • High CA125 levels increase the risk of conversion therapy failure (OR: 5.449, p=0.01).

For those with normal CA125 levels, consider early aggressive treatment paired with PD-1 inhibitors to improve chances of successful conversion therapy.

Journal Article by Zheng Z and Sun X in J Gastrointest Oncol

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