A novel risk model using stress granule-related gene signatures (sgrgs) shows promise for improving prognostic accuracy in pancreatic ductal adenocarcinoma (PDAC).
- Four key sgrgs (lama3, itga6, col17a1, top2a) were identified as significant predictors of PDAC prognosis.
- A nomogram combining age, N stage, and risk score demonstrated strong predictive capacity.
Understanding these markers can enhance patient selection for targeted therapies and improve outcomes in PDAC management.
- Immune profiling revealed links to M0 macrophages and CD8 T cells, which may inform treatment strategies.
Journal Article by Wang L, Zong L (…) Guan M et 2 al. in Int J Surg
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