Nissen fundoplication yields lasting relief for GERD, with high satisfaction rates over a decade or more.

• Heartburn decreased from 94.2% to 33.7%, regurgitation from 68.7% to 13.4%, and esophagitis from 61.7% to 7.4%.
• Only 17% experienced symptom recurrence, while 87% reported they would choose the procedure again.

Postoperative challenges include gas-bloating (53%) and dysphagia (26%), but overall outcomes support its effectiveness.