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EUS-guided RFA shows promise for managing IPMNs

Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) offers a safe, minimally invasive option for patients with branch-duct IPMNs who cannot undergo surgery.

  • Technical success reached 100% across 62 procedures, with local control in 98% of lesions.
  • Adverse events occurred in 27% of cases, mainly mild abdominal pain; no procedure-related deaths were reported.

This approach maintains pancreas-wide disease control in 80% of patients.

  • Smaller cysts and fewer worrisome features correlate with better outcomes.

Journal Article by Barras J, Lorenzo D (…) Barthet M et 2 al. in Gastrointest Endosc

Copyright © 2026 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

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