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Upper Gastrointestinal Tract ·

Improved Peritoneal Disease Detection in Advanced Gastric Cancer

Staging laparoscopy reveals peritoneal disease in over half of advanced gastric cancer patients, enhancing surgical decision-making.

  • Peritoneal disease was found in 54.9% of patients undergoing staging laparoscopy, with positivity rates of 61.7% in type 4 lesions.
  • The sensitivity and specificity of staging laparoscopy were 94.6% and 100%, respectively, demonstrating high diagnostic accuracy.

The four-factor predictive score aids in patient selection, increasing the potential to tailor surgical interventions based on individual risk.

  • Risk factors include elevated CA19-9 and CA125 levels and specific tumor histologies, with disease incidence ranging from 32.4% to 100% based on score.

Journal Article by Kudou K, Irino T (…) Nunobe S et 2 al. in Br J Surg

© The Author(s) 2026. Published by Oxford University Press on behalf of BJS Foundation Ltd. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.

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