Robotic multivisceral resection is feasible and beneficial for select patients with locally advanced gastroesophageal junction tumors.

• A 6.3-cm T4BN2 adenocarcinoma was successfully resected within 6 hours post-neoadjuvant FOLFOX chemotherapy.
• The approach allowed for R0 resection while maintaining quality of life through careful patient selection and technique.

Surgical teams should consider this method for eligible patients to enhance recovery and early systemic therapy resumption.

• Key measures included hand-sewn esophagojejunostomy and meticulous defect closure to prevent complications.