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Upper Gastrointestinal Tract ·

Lymph Node Yield Impacts Outcomes in Esophageal Cancer Surgery

Higher lymph node yield after neoadjuvant chemoimmunotherapy improves disease-free survival in esophageal squamous cell carcinoma, guiding surgical practices.

  • Patients with no residual disease (ypt0-2n0) saw improved survival with 20-30 lymph nodes; benefits plateau beyond this range.
  • In cases with residual disease (ypn1-3), higher yields correlated with longer disease-free survival.

Improving lymph node dissection may serve as a key quality indicator in surgical decision-making for this patient population.

  • Lower lymph node yields consistently linked to worse disease-free survival across all stages.

Journal Article by Lv H, Wang Z (…) Tian Z et 16 al. in Ann Surg Oncol

© 2026. The Author(s).

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