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Perspectives, Opinions and Curiosities ·

Prehabilitation Alters Immune Response in Abdominal Cancer Surgery

Multimodal prehabilitation may not significantly impact postoperative immune function, but it leads to a less inflammatory state before surgery.

  • 130 patients studied: 102 received prehabilitation, 28 usual care.
  • Pro-inflammatory cytokine production decreased, while IL-10 levels increased after prehabilitation.

Consider prehabilitation for optimizing patients pre-surgery, but be cautious of its limited postoperative immune benefits.

  • No significant immune differences on postoperative day one between groups.

Journal Article by Jacobs LMC, Drager LD (…) Warlé MC et 6 al. in Br J Surg

© The Author(s) 2026. Published by Oxford University Press on behalf of BJS Foundation Ltd.

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