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Intestine and Lower Gastrointestinal Tract ·

Transanal TME delivers strong outcomes for rectal cancer

Transanal total mesorectal excision (TATME) shows promising long-term results for patients with low rectal cancer.

  • Three-year overall survival at 93.7%, disease-free survival at 84.6%.
  • 97% of patients remained stoma-free at 3 years, enhancing quality of life.

Consider TATME for resectable mid and low rectal tumors; ongoing monitoring of long-term outcomes remains essential.

  • Significant late complications in 32% of patients, with 21 classified as severe (Clavien-Dindo ≥3).
  • Recurrence linked to preoperative N stage, lymph node yield, tumor deposits, and perineural invasion.

Clinical Trial, Phase II by Donovan KF, Carmichael H (…) Sylla P et 18 al. in Ann Surg

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