Patients with colorectal cancer receiving cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy (CRS plus HIPEC) experience significantly improved quality of life (QoL) compared to those undergoing CRS alone. Results indicate a notable minimal clinically important difference (MCID) favoring the HIPEC group, with improvement often evident within three months. Deterioration in MCID correlates with factors such as […]
Author: STITCHES Newsletter
Expert Consensus Establishes Guidelines for Sleeve Gastrectomy Practices
An international panel reached a consensus on sleeve gastrectomy, endorsing its use for diverse patient populations, including adolescents and the elderly. Key recommendations included avoiding routine dissection of the hiatus and prioritizing endoscopic pigtail drainage for managing acute leaks. Additional surgical options were outlined for patients with severe gastroesophageal reflux disease (GERD) and inadequate weight […]
Indocyanine Green Imaging Enhances Long-Term Survival in Gastric Cancer Surgery
In a pivotal 5-year follow-up of the FUGES-012 trial, patients who underwent indocyanine green (ICG) fluorescence-guided laparoscopic lymphadenectomy for gastric cancer exhibited significantly improved overall survival and disease-free survival compared to the non-ICG cohort. The ICG group also showed fewer recurrences, with a notable reduction in locoregional recurrences and an earlier recurrence peak in the […]
Advanced dynamic models improve survival predictions in colorectal cancer liver metastases
Dynamic prognostic models for colorectal cancer with liver metastases significantly enhance survival predictions by integrating longitudinal laboratory markers. In a cohort of 976 patients, the most effective model outperformed static approaches, achieving area under the curve (AUC) values of 0.850 for five-year progression-free survival and 0.849 for overall survival. A web-based tool has been developed […]
Real-time lymphatic mapping could redefine colon cancer surgery margins
A phase II trial aims to assess the effectiveness of indocyanine green (ICG) fluorescence-guided lymph node mapping in determining bowel resection margins for patients with colon cancer. By tailoring lymph node dissection based on individual anatomy, the approach seeks to balance extensive dissection and potential complications while optimizing oncological outcomes. If sensitivity exceeds 96% after […]
Prehabilitation Program Cuts Postoperative Complications for Sarcopenic Liver Surgery Patients
A 6-week multimodal prehabilitation program significantly slashed postoperative morbidity in patients with sarcopenia undergoing major hepatectomy. The prehabilitation group experienced a mere 13.3% complication rate compared to 50% in the standard care arm, translating to a 36.7% absolute risk reduction. All major complications occurred in the control group. Beyond lowering complications, the program also enhanced […]
Salivary Pepsin Testing Reveals Key Reflux Factors Post-Esophagectomy
Salivary pepsin testing objectively tracks reflux trajectories in post-esophagectomy patients. The study identifies redundancy of conduit as a significant risk factor for increased reflux, while maintaining a semi-fowler position and pre-sleep fasting for at least two hours offers protective benefits. These findings highlight essential modifiable elements that can enhance recovery pathways for patients, aiming to […]
Robotic NICE procedure cuts costs in colorectal surgery significantly
The robotic NICE procedure delivers superior cost-effectiveness in left-sided colorectal resections, showing a median direct cost of $9,946—well below laparoscopic ($16,389), robotic ($14,473), and open surgery ($10,427). Total costs mirror this trend, with NICE at $22,263, contrasted with $29,324 for laparoscopic, $32,908 for robotic, and $22,915 for open. Adjusted analyses reveal NICE results in up […]
Mobile App Enhances Bowel Preparation Compliance and Quality for Colonoscopy
A mobile app for bowel preparation training outperformed standard instructions in ensuring compliance and quality among colonoscopy patients. In a trial of 160 adults, those using the app achieved a 94.9% adequacy rate compared to 83.8% for the control group. Compliance with dietary protocols also surged, and patients reported fewer difficulties. Anxiety levels, however, remained […]
New lymph node classification systems outperform AJCC in predicting gastric cancer survival
Log odds of positive lymph nodes (lodds) and positive lymph node ratio (lnr) demonstrate superior predictive capabilities for survival in gastric signet ring cell carcinoma (gsrc) patients compared to the traditional AJCC n-category. Multivariate analysis reveals both lodds and lnr as significant prognostic factors, with improved sensitivity and specificity in predicting outcomes at 1, 3, […]