High-volume centers in the USA saw positive results with Transanal Total Mesorectal Excision (TaTME) for rectal cancer. The study of 391 patients revealed low rates of local recurrence, high completion rates of TME specimens, and promising 3-year overall survival. These findings support the oncologic safety and perioperative benefits of TaTME when conducted by skilled surgeons […]
Author: STITCHES Newsletter
Pylorus Preservation in SG + LoopDJB Reduces Hypoalbuminemia Compared to OAGB
One anastomosis gastric bypass (OAGB) and sleeve gastrectomy with loop duodenojejunal bypass (SG + LoopDJB) demonstrate similar weight loss, type 2 diabetes remission, and lipidemia improvements at 1 year post-operation. OAGB presents higher hypoalbuminemia but lower gastroesophageal reflux disease symptoms compared to SG + LoopDJB. Pylorus preservation in SG + LoopDJB may reduce hypoalbuminemia risk, […]
Left-Sided Colon Cancer Shows Better Survival Than Rectal Cancer Post-Hepatic Metastasectomy
Survival outcomes differed between left-sided colon and middle/low rectal cancer post-colorectal hepatic metastasectomy. Patients with left-sided colon cancer exhibited significantly better overall survival (OS) than those with middle/low rectal cancer, especially in the subgroup analysis of ras mutations. The study suggests that middle/low rectal cancer should not be grouped together with left-sided colon cancer in […]
Whipple Over the Splenic Artery (WOTSA) as an Alternative to Total Pancreatectomy for PDAC
Whipple over the splenic artery (WOTSA) can replace most total pancreatectomies for ductal adenocarcinoma, offering similar complication rates but improved postoperative glycemic status and potentially better disease-free survival. Results show no reoperations required in the WOTSA group due to pancreas or spleen issues, with comparable operative outcomes to total pancreatectomy. Findings suggest WOTSA as a […]
Colorectal Carcinoma In Situ Can Metastasize and Recur
Colorectal carcinoma in situ can metastasize to lymph nodes and recur, challenging previous assumptions. Among 1069 patients, 0.46% experienced regional lymph node metastasis or recurrence, with cases identified during or after primary surgery. Distant metastases were also observed, emphasizing the need for careful assessment at diagnosis. This study highlights the importance of recognizing potential metastasis […]
Diagnostic Accuracy of Ultrasonography and Non-Contrast Computed Tomography in Acute Appendicitis
Ultrasonography and non-contrast computed tomography show high accuracy in diagnosing acute appendicitis, reducing negative laparotomy rates without increased risks. Computed tomography is superior to ultrasonography. The study compared sensitivity, specificity, and accuracy of both methods, indicating CT as a valuable second-line tool. With proper utilization of these imaging techniques, clinicians can effectively diagnose appendicitis and […]
Comparing Laparoscopic-guided vs Ultrasound-guided TAP Block in Cholecystectomy
Ultrasound-guided TAP block is often preferred, but laparoscopic-assisted TAP (LTAP) shows shorter administration time. Post-operative pain management, analgesic requirements, and nausea were similar between LTAP and ultrasound-assisted TAP (UTAP) groups. However, UTAP group had reduced nausea and vomiting instances. LTAP block is a viable alternative in the absence of ultrasound guidance, offering quick and efficient […]
Higher Chemotherapy Dose and Muscle Mass Improve Pancreatic Cancer Survival
Study finds higher relative dose intensity (RDI) of adjuvant S-1 chemotherapy and greater psoas muscle mass volume (PMV) linked to significantly improved 5-year overall and relapse-free survival rates in patients with resected pancreatic ductal adenocarcinoma. RDI emerges as an independent prognostic factor, with patients displaying high RDI and high PMV showing the best outcomes. Combining […]
Consensus Supports Robotic HPB Surgery for Minimally Invasive Indications
Robotic surgery in hepato-pancreatic-biliary procedures is feasible and valuable for minimally invasive indications. Expertise is crucial for safety, encompassing requirements for credentialing in robotics. Prioritized questions for future trials include prospective registries with validated outcome metrics. The consensus guidelines from the Robot4HPB conference highlight state-of-the-art expertise and encourage safe use and promotion of robotic procedures […]
Evolutionary Paths and the ‘Bad Apple’ Effect in Hepatocellular Carcinoma
An atlas of hepatocellular carcinoma revealed seven genetic evolutionary paths influencing patient clinical trajectories. Most notably, the ‘bad apple’ effect showed that the aggressive cell fraction within tumors predicted prognosis better than overall heterogeneity levels, reshaping how clinicians predict survival. This study highlights the importance of tumor evolution in prognosis post-surgery and suggests personalized therapies […]