In recent years, there has been an increased use of minimally invasive surgery (MIS) for adrenocortical carcinoma (ACC). However, MIS has been associated with noncurative resection and locoregional recurrence. This study aimed to identify risk factors for margin-positive resection in ACC patients undergoing MIS. Factors such as increasing age, nonacademic center, advanced tumor stage, and […]

A multicenter retrospective study reports that ultrasound-guided thermal ablation (TA) is an effective and safe treatment option for patients with solitary low-risk papillary thyroid microcarcinoma (PTMC). Over a median follow-up period of 77.2 months, the incidence of disease progression, lymph node metastasis, and recurrent tumors were 3.6%, 1.1%, and 2.5%, respectively. TA achieved a median […]

In a Swedish cohort of 1636 total thyroidectomy patients, researchers found an alarming 8.7% developed permanent hypoparathyroidism. Notably, 23.2% with low parathyroid hormone levels post-surgery faced a 6.7% risk of permanency. Critically, discrepancies between quality registers and comprehensive chart reviews signal underestimation of the condition’s prevalence. Overtreatment concerns arise due to inadequate attempts to cease […]

In a study spanning 2016 to 2021, 231 patients underwent parathyroidectomy for primary hyperparathyroidism. Preoperatively, 32% had prediabetes, and 47% had insulin resistance. Twelve months postoperative, insulin resistance significantly decreased in both prediabetes (-0.69; p = .04) and insulin resistance groups (-0.85; p < .001). In prediabetes patients, 64% reduced insulin resistance, with 31% achieving […]

Robotic posterior retroperitoneal adrenalectomy and lateral transperitoneal adrenalectomy were compared using a 1:1 matched propensity analysis. In 154 matched cases, no significant differences were found in operative time, conversion to open surgery, postoperative pain, morphine use, length of stay, or 90-day complications. While posterior retroperitoneal adrenalectomy had lower estimated blood loss, it was not considered […]

A study introduced a preoperative calcium challenge for patients with elevated parathyroid hormone and normal calcium levels. Of 29 patients, 55% normalized parathyroid hormone with persistent normocalcemia, confirming secondary hyperparathyroidism. In 19%, classic primary hyperparathyroidism was diagnosed. Short-interval calcium supplementation revealed ∼50% resolved secondary hyperparathyroidism due to low calcium intake, avoiding unnecessary surgery. This approach, […]

In the thyroid cancer arena, the study unveils the tricky identity crisis of anaplastic thyroid carcinoma (ATC). Often emerging from differentiated thyroid carcinoma (DTC), ATC’s rebel nature complicates diagnosis. Researchers scoured 36 cases, discovering ATC’s deceptive biomarker profile. While TTF1 stays mum, PAX8 and divergent markers like GATA3 and SATB2 stage a confusing spectacle. These […]

Researchers spill the tea on their fresh Enhanced Recovery After Surgery (ERAS) pathway for thyroid/parathyroid surgeries. The vibe? ERAS brings the party with a significant cut in recovery time (9.2 to 7.5 hours) and a drop in patient-initiated admissions. The ERAS group flaunts lower morphine doses and daily pain scores, proving this pathway’s worth for […]

In the quest for parathyroid precision, researchers unveil the potential of near-infrared autofluorescence (NIRAF) overlay imaging. 189 surgical contenders underwent the spotlight, revealing 543 parathyroid glands (PGs). Results? A tiebreaker, with surgeons and overlay imaging each spotting PGs in 111 cases. The NIRAF playbook dictates a sweet spot: 8-12 cm distance, a 90° angle, and […]

In the world of adrenal gland dilemmas, researchers delve into the showdown between total adrenalectomy and its hip sibling, subtotal adrenalectomy, for bilateral pheochromocytoma. Analyzing 10 studies with 1202 patients, they uncover that subtotal adrenalectomy, while saving from adrenal insufficiency, packs a punch with a higher recurrence rate (14.1% vs. 2.6%) and lower post-surgery steroid […]