In the thyroid cancer arena, the study unveils the tricky identity crisis of anaplastic thyroid carcinoma (ATC). Often emerging from differentiated thyroid carcinoma (DTC), ATC’s rebel nature complicates diagnosis. Researchers scoured 36 cases, discovering ATC’s deceptive biomarker profile. While TTF1 stays mum, PAX8 and divergent markers like GATA3 and SATB2 stage a confusing spectacle. These […]
Category: Endocrine Surgery
Rockin’ Recovery: Find Success with ERAS Pathway for Thyroid and Parathyroid Procedures
Researchers spill the tea on their fresh Enhanced Recovery After Surgery (ERAS) pathway for thyroid/parathyroid surgeries. The vibe? ERAS brings the party with a significant cut in recovery time (9.2 to 7.5 hours) and a drop in patient-initiated admissions. The ERAS group flaunts lower morphine doses and daily pain scores, proving this pathway’s worth for […]
Parathyroid Precision: NIRAF Overlay Imaging Emerges as a Surgical Sidekick
In the quest for parathyroid precision, researchers unveil the potential of near-infrared autofluorescence (NIRAF) overlay imaging. 189 surgical contenders underwent the spotlight, revealing 543 parathyroid glands (PGs). Results? A tiebreaker, with surgeons and overlay imaging each spotting PGs in 111 cases. The NIRAF playbook dictates a sweet spot: 8-12 cm distance, a 90° angle, and […]
Subtotal vs. Total Adrenalectomy in Bilateral Pheochromocytoma – Less Insufficiency, More Recurrence?
In the world of adrenal gland dilemmas, researchers delve into the showdown between total adrenalectomy and its hip sibling, subtotal adrenalectomy, for bilateral pheochromocytoma. Analyzing 10 studies with 1202 patients, they uncover that subtotal adrenalectomy, while saving from adrenal insufficiency, packs a punch with a higher recurrence rate (14.1% vs. 2.6%) and lower post-surgery steroid […]
Swallowing Woes Post-Thyroid Surgery: A Senior’s Struggle
Unveiling the scoop on older adults, researchers spill the tea on dysphagia after thyroid and parathyroid surgery. Surveying 175 patients, aged 65 on average, they found 77.7% reported pre-op swallowing troubles, 22.4% more in frail folks. Post-op, 43.4% and 49.1% faced worse scores at 3 and 6 months. Pre-op dysphagia meant a 3.07-fold risk of […]
Adrenal Cancer Secrets: Mixed Hormonal Tumors Spell Trouble
In a hip multicenter study, researchers spilled the tea on adrenal cancer secrets. Analyzing 807 patients, they unveiled that mixed cortisol/androgen-secreting adrenal tumors play hard on survival, with worse overall survival compared to solo cortisol or androgen secrets. Notably, after a clean R0 surgery, the secretory subtype didn’t sway overall survival. Cortisol-secreting tumors spilled more […]
High-Volume Parathyroid Surgeons: A Dearth in Accessibility
The hunt for equitable healthcare takes center stage as researchers uncover disparities in access to high-volume parathyroid surgeons in the US. Analysis of 2019 Medicare data reveals a skewed distribution, with 445 identified surgeons mostly concentrated in metropolitan areas. Shockingly, disadvantaged neighborhoods face longer distances to these specialists, potentially impacting treatment outcomes for hyperparathyroidism patients. […]
Social Vulnerability Delays Treatment: Impact on Primary Hyperparathyroidism Evaluation
In a Massachusetts study on primary hyperparathyroidism, researchers found that patients in socially vulnerable groups faced delays in surgeon evaluation, contributing to heightened risks of long-term complications. Among 1,082 patients, those in the highest vulnerability quartile had a 33% lower surgeon evaluation rate and were seen 67 days later than those in the lowest quartile. […]
Tumor Biology and Surgical Margins Dictate Survival in Non-Metastatic Adrenocortical Carcinoma: A Paradigm Shift
In the battle against adrenocortical carcinoma (ACC), researchers find surgical approach and extent matter less than tumor biology and margins in non-metastatic cases. A cohort study (2010–2019, 1,175 subjects) reveals laparoscopic surgery, often considered minimally invasive, correlates with worse survival in advanced disease (stage III). Positive margins negatively impact survival, while chemoradiation benefits those with […]
Surgery Shines: A Viable Treatment Avenue for Stage IE Primary Thyroid Lymphoma
Surgery emerges as a viable treatment for stage IE primary thyroid lymphoma (PTL), with a cohort study of 1,596 patients (SEER database) and an external cohort of 38 patients (Shanghai, China). The 7.8-year SEER analysis showed no significant survival difference between surgery, surgery + radiotherapy/chemotherapy, and radiotherapy/chemotherapy alone. In the external cohort, surgery-alone exhibited comparable […]
