Surgeons should note that preoperative treatment duration over six months significantly improves survival outcomes for patients undergoing conversion surgery for unresectable locally advanced pancreatic cancer. Patients receiving >6 months of preoperative treatment showed median overall survival of 50.4 months versus 29.7 months for those with ≤6 months (p<0.001). Identifying four key prognostic factors can stratify […]

Post-pancreatectomy acute pancreatitis is crucial in predicting complications after pancreatoduodenectomy. 24.3% of patients developed clinically relevant postoperative pancreatic fistula (cr-popf); 90-day mortality was 3.4% overall, spiking to 9.0% with cr-popf. Post-pancreatectomy acute pancreatitis (ppap) was linked to a 4.88 times higher risk of 90-day mortality, making it a key independent predictor. Surgeons can enhance patient […]

This study reveals key clinicopathologic insights into perihilar intraductal papillary neoplasms (IPNBs) and their association with invasive carcinoma, informing surgical management. Of 27 cases, 21 had associated invasive carcinoma, highlighting the high incidence of malignancy in patients. Median tumor size was 2.8 cm, with invasive tumor size averaging 1.2 cm. Understanding these characteristics can improve […]

Surgeons can now consider a new arterial reconstruction method for the left gastric artery (LGA) during distal pancreatectomy with celiac axis resection (DP-CAR). The common hepatic artery (CHA) can successfully supply the replaced left hepatic artery (RLHA), ensuring adequate blood flow. The procedure had an operative time of 215 minutes and only 35 ml of […]

This study reveals a liver surface-guided method that significantly improves success rates for the Pringle maneuver in minimally invasive repeat liver resections. Pringle taping success jumped from 33% to 91.4% with the new technique. Median operative time was 331.5 minutes with only 70 ml blood loss and a short 8-day hospital stay. This approach is […]

Waiting for surgery at high-volume centers yields better outcomes for pancreatic cancer patients than early surgery at low-volume centers. Patients at high-volume centers with longer waits (over 28 days) had a 5-year survival rate of 23%, compared to 19% at low-volume centers. Adjusted analysis shows a mortality hazard ratio of 0.81 for high-volume centers, indicating […]

A novel TNM staging system offers improved prognostic insight for intrahepatic cholangiocarcinoma, impacting surgical decision-making and patient outcomes. In a study of 496 patients, five-year survival rates surpassed 80% for specific tumor types (≤50 mm intraductal, ≤20 mm mass-forming without vascular invasion). The new system classified survival more accurately than the AJCC, especially for tumors […]

Adjuvant therapies significantly reduce recurrence risk in hepatocellular carcinoma patients after hepatectomy. Radiotherapy (RT) shows the best results for disease-free survival (HR 0.31) and overall survival (HR 0.31). Tyrosine kinase inhibitors (TKI) also improve outcomes but are less effective than RT (HR 0.48 for DFS, HR 0.50 for OS). Surgeons should consider RT as the […]

Minimally invasive parenchyma-sparing pancreatectomy (mi-psp) lowers the risk of new-onset diabetes and pancreatic exocrine insufficiency in patients with benign and low-grade pancreatic tumors. Postoperative diabetes occurred in 9.8% of mi-psp patients compared to 23% in the standard approach (p=0.008). The five-year cumulative risk of diabetes was 26.7% for mi-psp versus 38.9% for the traditional method. […]