Surgical resection without multimodal treatment for early-stage pancreatic cancer can lead to better survival outcomes. Upfront surgery showed a median overall survival of 14.09 months compared to 6.34 months for those who refused surgery. One-year survival rates were 56% with surgery versus 26% without. R0 resection patients had a median survival of 17.87 months, significantly […]
Category: HPB & Spleen
Novel Risk Score Predicts Pancreatic Fistula After Surgery
A new preoperative scoring system enhances risk stratification for clinically relevant postoperative pancreatic fistula (cr-popf) after pancreatoduodenectomy, potentially improving surgical outcomes. The 6-point score boasts an area under the ROC curve of 0.89, with 81.8% sensitivity and 91.7% specificity. cr-popf incidence is 4.6% in low-risk patients versus 82.5% in very-high-risk patients. Implementing this tool allows […]
Understanding Recurrence Patterns Post-Colorectal Liver Metastasis Surgery
Tailored postoperative surveillance can significantly improve outcomes for colorectal liver metastases patients. Among 962 patients, isolated liver recurrence was most common (49.7%) within 5 months. Bilateral disease showed higher risk with R1 resection (20.9% vs. 14.4%) and greater modified tumor burden scores (8.1 vs. 3.4). Surgeons should prioritize early, personalized follow-up, especially for high burden […]
Minimally Invasive Approach Shows Strong Outcomes for Gallbladder Cancer
Minimally invasive radical cholecystectomy provides promising long-term survival for gallbladder cancer patients. 222 suspected gallbladder cancer patients underwent minimally invasive surgery, revealing a median overall survival of 60 months. Early-stage (T1/T2) patients had a significantly higher median survival of 66 months versus 36 months for locally advanced (T3/T4) cases. Surgeons should consider this technique in […]
Perineural invasion worsens survival in resected pancreatic tumors
Patients with pancreatic neuroendocrine tumors (PNETs) and perineural invasion (PNI) face significantly worse outcomes post-surgery. PNI occurs in 24.4% of PNET patients and is linked to higher tumor grades and advanced disease stages. Patients with PNI have a median overall survival of 115.9 months, compared to no PNI patients whose median survival is not yet […]
Robotic Surgery Enhances Caudate Lobe Resection Outcomes
Robotic-assisted surgery significantly improves the feasibility of caudate lobe resections for hepatobiliary surgeons. Enhanced precision allows for better suturing and ligation of critical vessels. Effective management of liver mobilization and hemostasis is achievable with careful planning and advanced intraoperative techniques. Surgeons can consider robotic assistance as a viable option for tackling complex caudate lobe cases, […]
Revolutionary Prognostic Tool for Intrahepatic Cholangiocarcinoma
A novel grading system combining CA19-9, CA125, and CEA significantly improves prognostic accuracy for intrahepatic cholangiocarcinoma patients post-surgery. In a study of 535 patients, the combined 3c grade correlated with overall survival and recurrence-free survival, outperforming individual markers (p < 0.001). Tumor size and lymph node metastasis distinguished between 3c grade groups (p = 0.006). […]
New scoring tool predicts pancreatic fistula risk in surgery
A new preoperative risk score based on CT measurements can help surgeons predict clinically relevant postoperative pancreatic fistula (cr-popf) after pancreatoduodenectomy. 6-point score achieved an AUC of 0.89; sensitivity 81.8%, specificity 91.7%. Incidence of cr-popf varies widely: 4.6% in low-risk vs. 82.5% in very high-risk patients. Use this scoring system for better surgical planning and […]
Neoadjuvant Chemotherapy Boosts Survival in Intrahepatic Cholangiocarcinoma
Neoadjuvant chemotherapy followed by surgery significantly improves outcomes for potentially resectable intrahepatic cholangiocarcinoma compared to upfront surgery. Median overall survival is 52.9 months with neoadjuvant therapy versus 37.0 months with upfront surgery. Recurrence is delayed (34.6 months vs. 24.4 months) and fewer patients are at risk of death (46.4% vs. 75.3%). Five-year survival rates are […]
Tailored Prognostication with Deep Learning After HCC Resection
Using deep-learning models with CT imaging can significantly improve prognostication for patients after hepatocellular carcinoma surgery. Postoperative recurrence rates within 2 and 5 years are 52.6% vs. 18.5% and 78.9% vs. 46.7% in high-risk vs. low-risk groups (p < 0.001). 5-year mortality rates are 45.1% vs. 9.2% and 10-year rates are 87.1% vs. 43.2% (p […]