Hepatobiliary Pancreat Dis Int8 Oct 2024
A new prognostic nomogram has been developed to predict tumor recurrence in hepatocellular carcinoma (HCC) patients post-liver resection. Analyzing 726 patients, the research identified independent factors such as alpha-fetoprotein and portal vein tumor thrombosis affecting recurrence-free survival (RFS). The nomogram achieved strong predictive performance, with…
J Gastrointest Surg7 Oct 2024
The study assessed the ACS NSQIP Risk Calculator's accuracy in predicting postoperative complications based on surgery type and underlying liver disease. In a cohort of 376 patients, the calculator effectively predicted outcomes such as surgical site infections and mortality, but its accuracy diminished for those…
Hepatol Res7 Oct 2024
A novel resectability classification for hepatocellular carcinoma (HCC) categorizes patients into resectable, borderline resectable, and unresectable groups. Analysis of 409 patients showed that those classified as borderline demonstrated significantly worse progression-free and overall survival compared to resectable patients, with p-values indicating strong significance (p <…
BMC Surg6 Oct 2024
An artificial intelligence model effectively predicted "futile" surgeries in intrahepatic cholangiocarcinoma patients, utilizing ten preoperative factors. In a study of 827 cases, 378 (45.7%) experienced insufficient surgical outcomes, with notable rates of recurrence (78.6%) and mortality (21.4%) within 12 months. The model achieved high accuracy,…
J Clin Gastroenterol5 Oct 2024
A meta-analysis involving 2,978 patients confirms that endoscopic ultrasound-guided fine needle acquisition (EUS-FNA/B) is an effective method for diagnosing and pre-operatively grading pancreatic neuroendocrine tumors (PANNETs). The overall concordance rate with surgical grading was 0.77, with a notable increase in the G1 subgroup (0.88). Notably,…
Asian J Endosc Surg5 Oct 2024
The introduction of a modified pulley maneuver significantly improves surgical outcomes in minimally invasive liver surgery (MILS). By employing barbed sutures with nonabsorbable polymer and metal clips, this technique allows for three-time reuse of sutures and minimizes iatrogenic damage during liver transection. The approach enables…
Br J Surg4 Oct 2024
A multicentre study on colorectal liver metastases establishes that an intraprocedural minimum ablative margin of at least 5 mm significantly reduces the risk of local disease progression. With data from 400 ablated tumors across various institutions, findings reveal 3-year progression rates drop to below 1%…
Surg Endosc4 Oct 2024
A systematic review of 19 studies with 12,731 patients revealed that robotic pancreaticoduodenectomy (rpd) significantly outperformed laparoscopic pancreaticoduodenectomy (lpd) in key perioperative metrics. Findings included lower conversion rates (OR=0.58), reduced blood transfusions (OR=0.59), shorter hospital stays (MD=-0.54 days), and fewer postoperative complications such as pneumonia…
Endosc Ultrasound3 Oct 2024
A study evaluated the feasibility of EUS-guided fine-needle biopsy (EUS-FNB) for next-generation sequencing (NGS) in unresectable pancreatic ductal adenocarcinoma (PDAC). The technical yield of EUS-FNB met criteria in 48% of cases, while the molecular yield was remarkably high at 98%. This means that nearly all…
J Clin Gastroenterol2 Oct 2024
A systematic review and meta-analysis revealed that endoscopic ultrasound-guided biliary drainage (EUS-BD) is a safe alternative to ERCP transpapillary drainage (ERCP-TPD) for primary biliary drainage in patients with distal malignant biliary obstruction (DMBO). Among 815 patients analyzed, clinical and technical success rates were similar for…