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Hepatol Res13 Oct 2024

Persistent acute kidney injury worsens outcomes in liver surgery

In a study involving 990 liver resection patients, persistent acute kidney injury (AKI) was linked to significantly worse postoperative outcomes, including increased morbidity, extended hospital stays, and higher 90-day mortality rates. Among 384 patients with hepatocellular carcinoma, persistent AKI correlated with poorer overall survival, identified…

Hepatobiliary Pancreat Dis Int13 Oct 2024

Robot-assisted hemihepatectomy shows improved outcomes over laparoscopic approach

In a comparative study involving 96 patients, robot-assisted hemihepatectomy (rob-hh) demonstrated significant advantages over laparoscopic hemihepatectomy (lap-hh) via dorsal approach. Rob-hh resulted in reduced estimated blood loss (median: 100 ml vs. 300 ml), lower blood transfusion rates (4.9% vs. 29.1%), and fewer postoperative complications (26.8%…

World J Surg Oncol11 Oct 2024

New nomogram predicts postoperative survival in gallbladder cancer

A novel nomogram has been developed to predict postoperative survival in gallbladder cancer patients, incorporating eight critical factors including TNM stage and serum biomarkers. Performance metrics demonstrated consistent time-dependent concordance indices exceeding 0.70 and area under the curve surpassing 75% for 1-, 3-, and 5-year…

Updates Surg11 Oct 2024

Laparoscopic hepatectomy outperforms radiofrequency ablation for small tumors

A comparison of laparoscopic hepatectomy (LH) and radiofrequency ablation (RFA) revealed that LH provides significantly better overall survival (OS) and disease-specific survival (DSS) for small hepatocellular carcinoma patients. In matched cohorts, 1, 3, and 5-year OS and DSS rates favored LH over RFA. For tumors…

Ann Surg Oncol10 Oct 2024

Surgical intervention improves survival in liver-only gastric metastases

Analysis of 10,977 patients with gastric adenocarcinoma and liver-only metastases revealed that those undergoing primary tumor resection combined with liver metastasectomy experienced significantly longer median overall survival (18.6 months) compared to non-surgical treatment (6.5 months). The study indicates that surgical resection, especially in highly selected…

Am J Surg10 Oct 2024

MVI grading severity influences survival outcomes after liver resection

A multicenter study involving 233 early-stage hepatocellular carcinoma patients revealed that microvascular invasion (MVI) grading significantly affects long-term outcomes post-laparoscopic liver resection. Specifically, median overall survival (OS) was 84.9 months for M0, 40.1 months for M1, and 25.2 months for M2. Likewise, recurrence-free survival (RFS)…

J Surg Oncol10 Oct 2024

Significant disparities in treatment for locally advanced pancreatic cancer

Treatment trends for locally advanced pancreatic cancer reveal that 67.67% of patients received primarily chemotherapy, with notable improvement in surgical resection rates over time. However, 41.19% also received radiation, yet many patients went untreated or did not receive guideline-recommended treatment (GRT). Socioeconomic factors like race,…

Dig Liver Dis10 Oct 2024

Contrast-enhanced ultrasound enhances survival in liver metastases

In a study involving 130 patients with unresectable colorectal cancer liver metastases, the use of contrast-enhanced intraoperative ultrasound (ce-ious) significantly improved hepatic recurrence-free survival rates compared to standard intraoperative ultrasound alone. Specifically, the ce-ious group demonstrated a lower recurrence rate (hazard ratio 0.55), especially in…

Surg Endosc9 Oct 2024

Transatlantic disparities in minimally invasive pancreatoduodenectomy outcomes

An analysis of 44,076 pancreatoduodenectomy patients reveals significant variability in the adoption and outcomes of minimally invasive pancreatoduodenectomy (mipd) across North America, Germany, the Netherlands, and Sweden. Usage rates of mipd ranged from 0.1% in Sweden to 17% in the Netherlands, with higher rates attributed…

Dig Dis Sci9 Oct 2024

Endoscopic ultrasound effectively diagnoses unexplained bile duct dilation.

Endoscopic ultrasound (EUS) demonstrated significant diagnostic yield for patients with unexplained common bile duct (CBD) dilation, particularly among those with negative prior imaging. In a cohort of 109 patients, 41 tested positive for various conditions, including choledocholithiasis and chronic pancreatitis. Factors such as older age…