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In a multicenter trial, the use of radiation-emitting metallic stents (REMS) combined with hepatic arterial infusion chemotherapy (HAIC) significantly enhanced overall survival (10.2 months vs. 6.7 months) and time to symptomatic progression (8.6 months vs. 5.4 months) compared to self-expandable metallic stents (SEMS) with HAIC…
The liver immune status index (LISI) demonstrated strong predictive capabilities for postoperative outcomes in hepatocellular carcinoma (HCC) patients, particularly with vascular invasion. In a study of 1,337 hepatectomies, LISI effectively stratified patients into distinct risk groups, correlating significantly with established prognostic markers. Notably, LISI provided…
A nomogram designed to predict cancer-specific survival (CSS) in middle-aged patients with advanced hepatocellular carcinoma demonstrated significant accuracy. Analyzing data from 3,026 patients, independent risk factors linked to CSS included gender, marital status, AJCC stage, tumor size, and metastasis. The model achieved area under the…
In a study of 250 patients with pancreatic ductal adenocarcinoma undergoing pancreatoduodenectomy, higher modified 5-item frailty index (mFI-5) scores were linked to worse surgical outcomes. An mFI-5 score greater than 2 was independently associated with doubled mortality risk (HR 2.08), while median overall survival was…
A recent study highlighted that robotic-assisted laparoscopic cholecystectomy with transcystic common bile duct exploration enables quicker duct clearance and shorter hospital stays. Patients undergoing this one-stage approach experienced significantly lower times for CBD clearance (45.2 hours vs. 47.0 hours), reduced length of stay (3.9 days…
A structured robotic pancreatoduodenectomy (rpd) program was successfully initiated with virtual expert collaboration, demonstrating excellent perioperative outcomes. Over 68 patients underwent the procedure from August 2020 to December 2023, achieving a median operative time of 407 minutes, an estimated blood loss of 150 ml, and…
Stereotactic body radiation therapy (SBRT) has emerged as a viable treatment for hepatocellular carcinoma (HCC), particularly for patients with advanced stages. Recognized in clinical guidelines as effective against alternatives like radiofrequency ablation, SBRT demonstrates local control rates of 80-90%. Its role in downstaging unresectable tumors…
A novel nomogram incorporating YAP expression and clinical metrics has been developed to predict postoperative prognosis in hepatocellular carcinoma (HCC) patients. Researchers evaluated 262 patients post-partial hepatectomy and found that those with high YAP expression faced significantly poorer recurrence-free survival (RFS) and overall survival (OS)…
A study investigating postoperative pancreatic fistula (POPF) risk factors in 210 distal pancreatectomy patients revealed that a peritoneum to portal vein distance (PPD) of 68 mm serves as a significant predictor for POPF, outperforming the visceral fat area (VFA). Among the identified risk factors, CRP…
A comparative network meta-analysis revealed that EUS-CDS with lumen-apposing metal stents (LAMS) outperformed other drainage techniques for distal malignant biliary obstruction (DMBO). This method yielded the highest technical and clinical success rates, particularly after comparing with ERCP and EUS-CDS with self-expandable metal stents. Notably, the…
