Gene expression analysis revealed 236 common differentially expressed genes (DEGs) between COVID-19 and pancreatic cancer (PC) patients. Functional enrichment pointed to pathways linked to viral replication and tumorigenesis. Ten hub genes, including cyclin-dependent kinase 1 and aurora kinase B, were identified, along with 42 transcription factors and 23 microRNAs that regulate gene expression. This research […]

A novel nomogram, based on liver stiffness (ls) via 2D-sheared wave elastography and spleen area (spa), was developed to predict posthepatectomy liver failure (PHLF) in hepatocellular carcinoma patients. Analysis of 562 patients demonstrated superior diagnostic performance compared to conventional models, such as the MELD and ALBI scores. In the training cohort, the nomogram achieved an […]

In a systematic review of six randomized controlled trials involving 736 patients, the anterior approach with or without liver hanging maneuver demonstrated significant survival benefits over conventional techniques. Overall and disease-free survival rates improved markedly (HR: 0.65; p < 0.0001). Although associated with longer surgery times (WMD: 29.5 min; p = 0.004), this approach resulted […]

A retrospective analysis of 66,326 patients revealed that 25.3% of pancreaticoduodenectomies (PD) for non-metastatic pancreatic ductal adenocarcinoma were futile, defined as death within 12 months. Factors increasing futility included macroscopically positive margins, poor tumor differentiation, and N2 nodal stage. Conversely, systemic therapy, radiation, and neoadjuvant therapy reduced the likelihood of futility. In the subgroup receiving […]

The study details the technical aspects and surgical outcomes of laparoscopic anatomical right hepatectomy using a four-incision anterior approach. Key maneuvers included blocking the glissonean pedicle and ligation of critical vessels, with an emphasis on anatomical landmarks for liver section determination. Successful patient positioning and incision placement were noted as crucial for procedure success. The […]

Analysis of 1,137 cases revealed that total hospitalization costs for pancreaticoduodenectomy were notably higher compared to pancreatectomy and hepatectomy within the China Healthcare Security Diagnosis Related Groups system. Length of hospital stay was significantly longer for pancreaticoduodenectomy patients. While the costs of pancreaticoduodenectomy and pancreatectomy were comparable, both exceeded those of hepatectomy. These findings emphasize […]

A study analyzing surgical outcomes for robotic pancreatoduodenectomy (RPD) found that a surgeon with extensive laparoscopic pancreatoduodenectomy (LPD) experience can successfully navigate the RPD learning curve. Performance metrics indicated that operation times significantly decreased in the proficiency phase, starting from case 34, without increasing complications or estimated blood loss during the learning phase. The findings […]

Early postoperative CT imaging after pancreatectomy significantly improved patient outcomes. Among 370 patients studied, those receiving early scans had shorter hospital stays (17.05 days vs. 22.82 days, p = .0008) and lower mortality rates (0% vs. 11%, p = .02). Early imaging also emerged as the sole independent predictor of a postoperative length of stay […]

A unique single-site plus-two ports technique for reduced-port robotic pancreaticoduodenectomy (rprpd) was reviewed in fifty patients, demonstrating safety and feasibility. The median operative time was 351 minutes, with an estimated blood loss of 80 ml. All procedures were completed without conversion to open surgery, and major postoperative morbidity occurred in 12% of cases. The innovative […]