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HPB (Oxford)7 Sep 2024

Robotic hepatectomy proves more cost-effective than open surgery

A comparative analysis showed that robotic hepatectomy resulted in a shorter median length of stay (2 days vs. 3 days) and significantly lower major complication (0% vs. 8.2%) and readmission rates (3.3% vs. 11.5%) compared to open hepatectomy. Overall, total 90-day perioperative costs were reduced…

BMC Gastroenterol5 Sep 2024

New nomogram predicts outcomes for gallbladder cancer patients

A novel nomogram was developed to predict clinical outcomes for gallbladder cancer patients post-surgery, incorporating inflammatory and nutritional biomarkers. It identified carcinoembryonic antigen, albumin-bilirubin, and geriatric nutritional risk index as key prognostic factors. With a c-index of 0.793, the nomogram demonstrated superior predictive ability compared…

Ann Surg3 Sep 2024

Drain fluid amylase levels predict risk of postoperative complications

Assessment of drain fluid amylase levels on days one and three provides a reliable estimate of the risk for clinically relevant postoperative pancreatic fistula (CR-POPF) after pancreatoduodenectomy. A study of 923 patients showed that integrating both dfa1 and dfa3 into a predictive model yielded a…

Eur J Surg Oncol3 Sep 2024

Collaborative approach improves outcomes for rare cancer research

The ISGACA initiative successfully united over 60 medical centers globally, gathering data from 4,309 patients to enhance treatment strategies for non-pancreatic periampullary cancers. By establishing a structured methodology, the group facilitated nine publications, secured research grants, and initiated a prospective multicenter clinical trial. The collaborative…

Surg Laparosc Endosc Percutan Tech3 Sep 2024

Infrared fluorescence imaging enhances tumor margin accuracy in surgery

Utilization of near-infrared fluorescence imaging during laparoscopic hepatectomy significantly improved tumor identification and secured clear resection margins in colorectal liver metastasis. Of the 94 tumors, fluorescence imaging detected 56 (59.6%), resulting in a 96.6% clear margin success rate for the 59 patients studied. Pathological assessment…

Langenbecks Arch Surg2 Sep 2024

Predictive model identifies early recurrence risk in liver cancer patients

A simple predictive model for early recurrence of hepatocellular carcinoma (HCC) post-liver resection has been developed. Based on an analysis of 1,133 patients, five key prognostic factors—alpha-fetoprotein levels and AJCC stage—were identified. Among the cohort, 35.1% experienced early recurrence within two years, with respective two-year…

World J Surg Oncol2 Sep 2024

Total mesopancreas excision enhances surgical outcomes in pancreatoduodenectomy.

In a systematic review of 738 pancreatic head cancer patients, total mesopancreas excision (TMPE) significantly increased R0 resection rates (RR 1.24) and reduced overall (RR 0.53) and local recurrence rates (RR 0.39) compared to standard pancreatoduodenectomy. TMPE also reduced blood loss (MD -143.70 ml) and…

Hepatobiliary Surg Nutr1 Sep 2024

Adjuvant therapy improves recurrence-free survival in HCC patients

Camrelizumab plus apatinib in a real-world setting has shown significant benefits in recurrence-free survival (RFS) for patients with hepatocellular carcinoma (HCC) with microvascular invasion following radical resection. The comparison between adjuvant therapy (99 patients) and observation (172 patients) indicated a hazard ratio of 0.52 for…

Ann Surg31 Aug 2024

Computer vision algorithm outperforms experts in predicting SMA margin status.

A computer vision algorithm was developed to predict superior mesenteric artery (SMA) margin status in pancreatic ductal adenocarcinoma patients using preoperative CT scans. In a study involving 200 patients, the algorithm achieved a sensitivity of 0.43, outperforming radiologists (0.23) and surgeons (0.36). Specificity was high…