Computed tomography-based vascular burden index accurately predicts vascular resection and pathological vascular invasion in pancreatic cancer patients post neo-adjuvant chemotherapy. The study found that the vascular burden index values, specifically around adjacent arteries and veins, significantly predicted vessel resection and invasion. These indices, particularly the regression of vvbi and avbi, were independent prognostic factors for […]
Category: HPB & Spleen
Augmented Reality System Enhances 3D Visualization in Liver Surgeries
An augmented reality (AR) system for laparoscopic liver surgery shows promise in improving visualization of internal anatomy. The system achieved a mean registration time of 2.4 minutes and a high accuracy rate of 93.8% in aligning preoperative 3D models with real-time laparoscopic images. Evaluations by surgeons demonstrate that this AR technology could significantly enhance tumor […]
Immune and Oxidative Stress-Related Genes as Targets for mRNA Vaccines in Pancreatic Cancer
Identification of potential mRNA vaccine targets in pancreatic cancer patients using immune- and oxidative stress-related genes. A model incorporating ERAP2, MET, CXCL9, and AGT genes predicts patient prognosis more accurately than current models. ERAP2 aids immune activation and cancer immune evasion, MET regulates cancer cell proliferation and invasion, CXCL9 expression is linked to poor prognosis […]
3D Liver Reconstruction Enhances Surgical Planning and Accuracy
A systematic review of 47 studies involving 3D liver reconstruction highlights its benefits in liver surgery. 87.2% of studies used 3D reconstructions for preoperative planning, particularly for complex hepatectomies and liver grafts. The approach improved navigation and accuracy in 55.3% of cases, facilitated graft selection and vascular preservation in living donor liver transplants, and allowed […]
New Classification System Improves Laparoscopic Treatment of Extrahepatic Choledochal Cyst
A new classification system for extrahepatic choledochal cyst (ecc) has been established through imaging clustering, unveiling types A, B, C, and D. Significant differences in comorbidities and postoperative complications were found among the types. Factors like age, BMI, and stone presence impacted operative time. Machine learning-driven analysis facilitated this novel typology creation, shedding light on […]
Augmenter of Liver Regeneration Impacts Blunt Liver Trauma
The study explores the role of Augmenter of Liver Regeneration (ALR) in blunt liver trauma using a rat model. ALR levels in plasma and liver tissue showed significant fluctuations depending on the time post-trauma. Plasma ALR levels peaked at 30 minutes, while intact liver tissue ALR levels were highest at 15 and 30 minutes. Inflammation […]
Novel scoring system accurately predicts risk of failure to achieve textbook outcomes after hepatectomy for hepatocellular carcinoma
A multicenter study developed and validated a scoring system to predict the risk of not achieving textbook outcomes (non-TOS) following hepatectomy for hepatocellular carcinoma (HCC). The scoring system, based on factors like obesity, ASA score, Child-Pugh grade, tumor size, and extent of hepatectomy, accurately stratified patients into low, intermediate, and high-risk categories for non-TOS. The […]
Minimally Invasive Liver Surgery Outperforms Open Surgery in Surgical Outcomes
Minimally invasive liver resection (MILR) demonstrated superior outcomes compared to open surgery in a study of 260 patients. MILR, performed in 68% of cases, resulted in shorter operative times, less blood loss, lower rates of major complications and bile leaks, and reduced hospital stays. Despite a higher proportion of prior abdominal surgeries in the open […]
Subgrading of G2 Pancreatic Neuroendocrine Tumors Reveals Behaviorally Distinct Subsets
Subgrading G2 pancreatic neuroendocrine tumors into 2A (Ki67 3% to < 10%) and 2B (10% to ≤ 20%) identifies distinct subsets with different metastasis rates and aggressiveness. G2B cases show significantly higher rates of liver/distant metastasis, lymph node metastasis, and histopathologic signs of aggressiveness compared to G2A. G2B tumors behave similarly to G3, suggesting they […]
Laparoscopic segmentectomy using ICG fluorescent navigation shows superior outcomes
Laparoscopic segmentectomy using ICG fluorescence navigation with the negative staining method showed superior outcomes compared to open segmentectomy. Patients who underwent laparoscopic surgery experienced shorter operative times, reduced blood loss, and shorter hospital stays. Additionally, they had significantly fewer grade II and grade III or higher postoperative complications. These findings highlight the precision and safety […]