New radiomic prediction models effectively identify post-hepatectomy complications and early recurrences in hepatocellular carcinoma patients. Utilizing features from two-dimensional shear wave elastography, the comprehensive complication index (CCI) model achieved an AUC of 0.896, while the recurrence model reached 0.854. Key predictors included radiomic signatures, platelet count, age, and blood flow. These advancements enable targeted interventions […]
Category: HPB & Spleen
ERCP Triumphs in Treating Severe Acute Cholangitis
Endoscopic retrograde cholangiopancreatography (ERCP) outperformed percutaneous transhepatic biliary drainage (PTBD) in patients with severe acute cholangitis due to common bile duct stones. ERCP achieved definitive stone clearance in 92.1% of cases and enabled shorter hospital stays, with faster ambulation and reduced patient discomfort. Although both methods effectively lowered inflammation and pain, PTBD patients experienced significantly […]
New NTAA Model Transforms Prognosis for Liver Cancer Patients
The NTAA prognostic model redefines outcomes for BCLC stage B hepatocellular carcinoma (HCC) patients undergoing transarterial chemoembolization (TACE). Analyzing over 2,500 patients, it identified tumor size, number, alpha-fetoprotein levels, and albumin-bilirubin grade as key survival predictors. Dividing patients into low, intermediate, and high-risk groups revealed median survival rates of 68.1, 35.7, and 15.4 months, respectively. […]
EUS-BD Outperform BEA-ERCP in Complex Biliary Obstruction
In a multicenter study, endoscopic ultrasound-guided biliary drainage (EUS-BD) demonstrated superior efficacy to balloon enteroscopy-assisted ERCP (BEA-ERCP) for patients with surgically altered anatomy and unresectable malignant biliary obstruction. EUS-BD achieved a significantly higher technical success rate and shorter procedure times, while maintaining similar clinical success and adverse event rates. BEA-ERCP was identified as an independent […]
New Benchmarks for Liver Surgery in Colorectal Metastases
Liver resection demonstrates strong oncologic outcomes for colorectal liver metastases (CRLM), with a 90-day mortality rate below 5%. One-year overall survival (OS) rates exceed 85% for most patients, dropping to 78% for those with ten or more metastases. Five-year OS rates range from 28% to 67%, depending on tumor burden. These findings establish critical benchmarks […]
ALPPS mortality drops with IDEAL-guided global registry collaboration
Once considered dangerously high-risk, ALPPS has evolved from >15% to
Protease Inhibitors Could Prevent Bleeding After Pancreatic Surgery
Enzymatic interactions from pancreatic juice cause critical vascular damage post-surgery, leading to severe hemorrhage. A study on porcine models reveals that trypsin and chymotrypsin significantly weaken arterial walls when mixed with intestinal fluids. However, administering nafamostat mesylate, a protease inhibitor, effectively mitigates this histopathologic damage. This finding underscores the potential for localized delivery of inhibitors […]
Endoscopic Techniques Outperform Surgery for Necrotizing Pancreatitis
Infected necrotizing pancreatitis treatment benefits from endoscopic strategies, outperforming traditional surgical methods. The systematic review revealed that upfront endoscopic necrosectomy (uen) ranked highest, showing significantly lower mortality rates, fewer complications, and shorter hospital stays. Endoscopic step-up (esu) approaches also displayed favorable results. A cost-effectiveness analysis confirmed endoscopic methods as the most economical choice, with a […]
Microwave Ablation Shows High Efficacy for Liver Tumors
Surgical microwave ablation (MWA) proves to be a robust treatment for diverse liver tumors, with a low readmission rate of 6.5%. Analyzing 3,035 tumors across 1,416 patients over 16 years, median overall survival reached 3.9 years, varying by tumor type, while median recurrence-free survival stood at 2.2 years. Notably, MWA’s outcomes match or exceed those […]
Low Phosphate Levels Heighten Complications Post-Pancreatic Surgery
Postoperative hypophosphatemia affects a significant 77.9% of pancreaticoduodenectomy patients, correlating with a 66.3% complication rate. The lowest phosphate levels occur on day three post-surgery, linking diminished phosphate to complications like pancreaticojejunostomy leakage. Those with complications show hypophosphatemia at a striking 82.5%. Monitoring and managing phosphate levels could mitigate risks and enhance recovery outcomes. Observational Study […]