The hepatic blood supply, a crucial aspect of liver surgery and transplantation, has undergone significant reorientations in recent years. Despite advancements, gaps in our understanding persist, impacting outcomes in living donor liver transplantation. This review delves into the complexities of portal hemodynamics in liver disease, exploring its role in liver regeneration and transplantation. Journal Article […]
Category: HPB & Spleen
Comparison of Laparoscopic Liver Resection and Enucleation for Giant Hepatic Hemangioma
Laparoscopic liver resection was associated with less blood loss compared to enucleation in patients with high portal phase enhancement ratio. For patients with a portal phase enhancement ratio higher than 38.9%, the liver resection approach is recommended for giant hepatic hemangioma, while both approaches showed similar outcomes in patients with low portal phase enhancement ratio. […]
Radiofrequency Ablation Combined with Sorafenib for Liver Cancer with Portal Hypertension
Radiofrequency ablation combined with sorafenib significantly improves liver function and survival rates in liver cancer patients with portal hypertension. Among 100 patients, the combined therapy group showed a higher total effective rate (82.00%) compared to the control group (56.00%). Prognostic factors include Child-Pugh grade, tumor size (6-10 cm), hepatitis history, sorafenib use, cancer stage (IIIC), […]
Development of nomogram for Survival Prediction in Gastric Cancer Patients with Liver Metastasis
A nomogram was developed to predict overall survival and cancer-specific survival in patients with gastric cancer and liver metastasis, showing satisfactory performance. Factors influencing survival included age, chemotherapy, grade, metastasis sites, and treatment received. The nomogram can assist clinicians in planning follow-up and rehabilitation strategies for better outcomes and provide support to high-risk patient groups. […]
Factors influencing treatment strategies for small pancreatic neuroendocrine neoplasms
Study evaluates optimal treatment strategies for nonfunctioning small pancreatic neuroendocrine neoplasms, highlighting the impact of tumor size and grade on lymph node metastasis, recurrence, and survival. Personalized treatment approaches considering tumor grading are recommended for heterogeneous nf-spnens. Tumor size >20 mm for net-g1 and >10 mm for net-g2 or higher are suggested thresholds for surgical […]
Diagnostic Performance of Short MRI Protocols for IPMN Surveillance
Short MRI protocols demonstrate suitability for surveillance of intraductal papillary mucinous neoplasms (IPMNs). In a retrospective study, protocols with T1-weighted, T2-weighted, MRCP, and DWI sequences show high concordance with clinical decisions for IPMN management. Inter-observer agreement is substantial across different protocols. Short MRI protocols offer efficient surveillance methods for IPMN, facilitating timely and accurate patient […]
Feasibility and Safety of Hepatic Arterial Infusion Pump Chemotherapy for Colorectal Liver Metastases
Feasible and safe, hepatic arterial infusion pump chemotherapy combined with systemic chemotherapy (HAIP-SYS) for colorectal liver metastases (CRLMs) showed promising results in a phase II study in the Netherlands. With a completion rate of 90% for two cycles, it demonstrated favorable disease control rates at first radiological evaluation and six months post-treatment. Although some patients […]
Laparoscopic Liver Resection Shows Comparable Outcomes to Open Liver Resection for High Tumour Burden Colorectal Liver Metastases
Laparoscopic liver resection (LLR) matches open liver resection (OLR) in outcomes for ≥ 3 colorectal liver metastases (CRLM), showing similar morbidity, mortality, and survival rates. LLR offers shorter hospital stays, advocating its consideration for selected patients with high tumour burden disease. This study, analyzing 277 patients, demonstrates comparable major hepatectomy rates between LLR and OLR. Although OLR […]
Understanding Upper Gastrointestinal and Hepatopancreaticobiliary Surgery in New Zealand
New Zealand is a low-volume center for upper gastrointestinal surgery, with most complex procedures concentrated in national cancer centers. There is evidence of regionalization, where larger centers perform procedures more frequently. Palliative procedures are more widely performed, but indigenous Māori are less likely to be treated in designated cancer centers. The challenge lies in optimizing […]
Optimal Lymph Node Resection in IPMN-Derived Pancreatic Cancer
Optimal lymphadenectomy of ≥20 lymph nodes in IPMN-derived PDAC is associated with improved overall survival. A minimum of 10 lymph nodes is needed for accurate nodal staging. Specific optimal cut-offs were identified for different types of surgeries. Journal Article by Habib JR, Rompen IF (…) Daamen LA et 12 al. in Ann Surg Copyright © […]