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3D-printed models reduce intraoperative blood loss and postoperative complications, particularly bile leakage, in complex hepatobiliary laparoscopic surgeries. Patients guided by 3D models had significantly lower comprehensive complication index scores compared to the control group. Multivariable analysis confirmed 3D models as independent protective factors against complications.…
Increasing cases of non-hepatitis B and non-hepatitis C hepatocellular carcinoma (NBNC-HCC) prompt a comparison with hepatitis virus-associated HCC. A retrospective study of 1321 liver resections showed comparable operative outcomes and long-term survival between matched NBNC-HCC and HV-HCC groups. Independent prognostic factors for overall survival were…
During a study of 1056 patients undergoing laparoscopic hepatectomy, 75% achieved a textbook outcome (TO). Factors like age, ASA classification, and tumor characteristics influenced TO attainment. Notably, patients reaching TO showed improved survival rates, suggesting its importance in precision surgery and patient outcomes.
Neoadjuvant chemotherapy before pancreaticoduodenectomy with vascular resection led to improved disease-free survival in pancreatic cancer patients. Patients who received neoadjuvant chemotherapy had more favorable pathological outcomes, decreased vascular invasion, and completed chemotherapy more often. The neoadjuvant chemotherapy group exhibited a significant increase in disease-free survival…
Postoperative complications significantly impact patient outcomes in hepatocellular carcinoma. Patients with moderate/severe complications had worse recurrence-free survival compared to those with no/mild complications. Notably, low and medium alpha-feto protein-tumor burden score patients with complications had higher recurrence risks, whereas complications did not affect high score…
Local ischemic preconditioning (LIPC) and remote ischemic preconditioning (RIPC) were found to be superior to no-preconditioning in reducing postoperative serum transaminase levels in hepatectomy. There was no significant difference between the two methods in postoperative liver function and surgical outcomes. RIPC showed potential benefits in…
Liver transplant (LT) was associated with improved long-term survival compared to liver resection (LR) in patients with multifocal hepatocellular carcinoma (MHCC). Factors such as race, insurance status, and treatment facility influenced the likelihood of receiving LT. This study highlights the clinical and sociodemographic disparities between…
Analysis of 500 robotic hepatectomies revealed significant number of cases needed to achieve mastery in minor, major, and technically challenging resections. Surgeons can utilize this data to enhance patient safety and outcomes, providing valuable insights for those gaining experience in robotic hepatectomies. The findings highlight…
Personalized circulating tumor DNA monitoring using a tumor-informed assay significantly improves recurrence surveillance and management in patients with colorectal liver metastases. Detectable ctDNA at specific time points post-surgery is associated with higher recurrence risk, serving as an independent prognostic marker. Longitudinal ctDNA analysis accurately predicts…
Resection margin width significantly influences overall survival post liver resection for colorectal liver metastasis. A cohort study of 754 patients revealed poorer survival with margins of 0-0.9mm compared to ≥1mm, even in the era of modern chemotherapy. Narrow margins (
