In a cohort of 769 hepatocellular carcinoma survivors, 21.6% experienced late recurrence post-treatment. Key findings showed that patients with late recurrence exhibited a higher fib-4 index (median 2.31) and a tendency toward microvascular invasion. Both factors were independently associated with worse recurrence-free survival (RFS). Patients identified as high-risk had a two-fold increase in recurrence hazard […]
Category: HPB & Spleen
Deep learning model enhances 3D segmentation of pancreatic cancer
A newly developed deep learning auto-segmentation model effectively segments pancreatic cancer and surrounding structures to assist surgical planning. In a study involving 275 patients, the model achieved a Dice similarity coefficient of 75.4 in internal and 75.6 in external validation. High segmentation accuracy was noted in the pancreas parenchyma but lower in pancreatic cancer lesions. […]
Endoscopic techniques improve outcomes for biliary leak management
Endoscopic management has emerged as a key strategy for treating biliary leakages resulting from surgery or trauma. Researchers emphasize the importance of accurately classifying leaks to choose appropriate treatments, which range from conservative care to surgical intervention. Notably, endoscopic techniques, especially endoscopic retrograde cholangiopancreatography with sphincterotomy and stent placement, are now favored for accessible leaks, […]
AI Enhances Early Detection of Pancreatic Cancer
Findings indicate that AI-driven imaging models significantly improve the detection of pancreatic ductal adenocarcinoma (PDA) through advanced radiomics and deep learning techniques. These models can identify subtle pre-diagnostic signs on CT scans months to years before clinical symptoms arise, addressing current limitations in sensitivity and interobserver variability. Although AI presents a promising avenue for earlier […]
Imaging Techniques Enhance Postoperative Management After Pancreatic Surgery
A narrative review underscores the significance of radiological assessments following pancreaticoduodenectomy in detecting postoperative complications. Utilizing cross-sectional imaging, particularly contrast-enhanced computed tomography, allows for prompt diagnosis and better patient outcomes. The review highlights the complementary role of magnetic resonance imaging in identifying specific biliary and pancreatic duct issues. It calls for a multidisciplinary approach among […]
Augmented reality improves surgical outcomes in liver cancer patients
A study evaluating augmented reality navigation combined with indocyanine green fluorescence in laparoscopic right hemihepatectomy found that this approach significantly reduced intraoperative blood loss (150 ml vs 250 ml) and lowered blood transfusion rates (13.5% vs 39.5%). Additionally, it improved one- and three-year recurrence-free survival rates (81.1% and 73.0% vs 60.5% and 50.0%, respectively). These […]
New risk score predicts recurrence in liver transplant for cancer
A novel risk score, PRETREAT, was developed to estimate post-transplant recurrence in patients with perihilar cholangiocarcinoma (pcca) following neoadjuvant therapy and liver transplantation. In a study involving 399 patients, the five-year recurrence rate was 29.7% in the development cohort and 27.6% in the validation cohort. Four predictors—residual tumor, vascular encasement, lymphovascular invasion, and tumor diameter—were […]
New CAP Score Predicts Liver Surgery Mortality Risks
A novel CAP score, combining type-IV collagen, albumin, and prothrombin time, effectively predicts 180-day surgery-related mortality in liver resection for hepatocellular carcinoma. With a predictive accuracy (AUC: 0.728), the score identifies risk levels in patients, showing mortality rates of 0.8% for low risk to 26.7% for high risk. It outperforms other existing models, underscoring its […]
AI-assisted system improves biliopancreatic disease detection
A novel AI-assisted endoscopic ultrasound (EUS) system demonstrated superior performance in recognizing biliopancreatic stations and segmenting anatomical structures. Testing with 45,737 EUS images revealed the mean teacher algorithm achieved 95.60% accuracy in internal tests and 92.72% in external validation for station recognition. Additionally, U-Net v2 emerged as the optimal model for segmentation. Notably, the system […]
Enhanced Recovery Protocols for Cirrhotic Liver Surgery Identified
A systematic review evaluated enhanced recovery after surgery (ERAS) protocols specifically for cirrhotic patients undergoing hepatectomy. From 3,123 screened articles, 81 were analyzed, revealing five perioperative items with moderate or high evidence levels. Key recommendations include preoperative ascites control, postoperative venous thromboembolism prophylaxis if coagulation tests are normal, avoidance of systematic drainage, preference for acetate-buffered […]