Surgeons can now better identify patients who may not benefit from surgery for gallbladder cancer. 11.1% of patients experienced ‘futile surgery’ with a median survival of only 8.9 months. Those who received successful surgical intervention had a median survival of 88.7 months (p < 0.001). Incorporating this nomogram into preoperative decision-making may significantly reduce unnecessary […]

A new meta-analysis shows the Albumin-Bilirubin (ALBI) score is crucial for predicting survival and liver function in hepatocellular carcinoma patients treated with transhepatic arterial chemoembolization (TACE). Higher ALBI grades significantly correlate with shorter overall survival: 2nd vs. 1st grade (1.52 times higher risk); 3rd vs. 1st (2.67 times); and 3rd vs. 2nd (1.94 times). The […]

Preoperative and postoperative multidrug-resistant bacteria significantly impair recovery after pancreatic surgery. 20.75% of patients tested positive for multidrug-resistant bacteria, linked to higher complications like pancreatic fistula (37.84% vs. 3.92% in MDR-negative). Key outcomes such as major complication rates, ICU stay, and overall hospitalization increased for MDR-positive patients (all p < 0.0001). Consider preoperative decolonization and […]

Optimal lymphadenectomy and adjuvant capecitabine boost survival for gallbladder cancer patients. Patients with ≥6 lymph nodes resected had a 68% lower risk of death compared to those with inadequate lymphadenectomy. Adjuvant capecitabine led to a 48% increase in disease-free survival and a 67% improvement in overall survival. Use these findings to prioritize thorough lymphadenectomy and […]

Pancreatic cancer in sub-Saharan Africa is largely diagnosed in advanced stages, severely affecting surgical outcomes. Over 80% of patients present with advanced or metastatic disease, limiting curative interventions. Surgical resections occur in less than 10% of cases, with palliative bypass as the primary procedure. Improving outcomes hinges on addressing healthcare disparities and investing in infrastructure […]

A new model predicts postoperative complications in hepatectomy patients, helping surgeons identify high-risk individuals and improve outcomes. An overall complication rate of 46.61% was observed in 1,350 cases. The model shows strong predictive power with an 86.9% sensitivity and a 9.36% estimated risk of severe complications for patients scoring 36. This tool can refine preoperative […]

Single-port robotic liver resections are feasible and safe, even in moderate-volume centers. 20 patients underwent surgery with no conversions to multiport/open approaches. Median operative time was 201.1 minutes with a 7.2-day hospital stay; no major complications occurred. These results suggest that surgeons can confidently adopt this technique for both major and minor hepatectomies. All malignant […]

Laser-activated nanoparticles can enhance immune response by transforming the tumor microenvironment in cholangiocarcinoma. Combining photothermal therapy with PD-1 blockade significantly reduced extracellular matrix stiffness and improved T-cell infiltration. This dual approach shifted tumors from immune-cold to immune-hot states, enhancing anti-tumor responses and reducing immunosuppressive signals. Surgeons should consider these findings to inform patient selection and […]