Biliary strictures, often resulting from various causes, disrupt bile flow and lead to significant complications. Traditional surgical methods are now complemented by advanced strategies, including molecular therapies targeting fibrosis pathways, gene-editing technologies, and tissue-engineered scaffolds. These approaches promise improved, safer treatment options tailored for precision medicine, addressing the complex pathology and enhancing outcomes for patients […]

Minimally invasive liver surgeries demonstrate significant benefits over open resections, especially in advanced cases. Among 686 patients, robotic-assisted procedures reduced major complications to 8%, compared to 17% for laparoscopic and 23% for open surgeries. Both laparoscopic and robotic approaches showed lower blood loss and shorter hospital stays across various difficulty levels, emphasizing their safety and […]

Implementing the Enhanced Recovery After Surgery (ERAS) protocol significantly enhances perioperative outcomes in robotic hepatectomy. A study of 544 patients revealed reduced estimated blood loss—from 214.7 to 141.7 mL—and a drop in 90-day readmission rates from 22.6% to 13.4%. Notably, post-ERAS patients presented higher rates of coronary artery disease and hypertension, yet experienced better overall […]

Percutaneous catheter drainage (PCD) significantly outperformed percutaneous aspiration (PA) in treating liver abscesses. PCD demonstrated higher treatment success rates and led to quicker clinical improvements, reducing recovery time by nearly two days. Additionally, PCD lowered the six-month recurrence rate by 56%. Both methods displayed comparable complication rates. These findings underscore PCD’s effectiveness and safety, calling […]

Venous thromboembolism (VTE) affects 15.6% of pancreatic cancer patients, significantly higher than other malignancies. Key risk factors include tumor location in the body or tail, poorly differentiated tumors, stage IV disease, metastasis, and elevated D-dimer levels post-surgery. The study’s findings emphasize the need for early identification and management strategies for these high-risk patients to prevent […]

Female patients demonstrated significantly better surgical outcomes following pancreatectomy compared to males, with 62.3% of women achieving ideal outcomes versus 54.1% of men. Women faced fewer complications, lower reoperation rates, and reduced 30-day mortality. The likelihood of achieving optimal results was notably higher for women and those undergoing distal pancreatectomy versus pancreatoduodenectomy. These findings suggest […]

Primary liver cancer (PLC) incidents surged 74% from 2000 to 2021 among adults aged 55+, with deaths rising 67% and disability-adjusted life years (DALYs) increasing 59%. While the annual incidence rates are projected to initially fall, projections indicate continuous case increases through 2050, especially in those 75 and older. Notably, non-alcoholic steatohepatitis and alcohol-related PLC […]

Hepatic arterial infusion pump (HAIP) chemotherapy delivers targeted therapy directly to the liver, markedly improving survival outcomes in liver-confined colorectal metastases (CRLM) and intrahepatic cholangiocarcinoma (ICCA). In unresectable CRLM, five-year overall survival rates reach 50%. Adjuvant HAIP after tumor resection shows two-year survival of 86%, compared to 72% with systemic therapy alone. ICCA patients benefit […]