A preoperative weight loss program significantly improves outcomes for colorectal cancer patients with excess weight. 61% of patients in the diet intervention lost 5% or more of their weight, compared to just 9% in usual care (odds ratio 16.8). Average weight loss in the intervention group was 6.1 kg, 4.3 kg more than controls. Patient […]
Category: Intestine and Lower Gastrointestinal Tract
Robotic Surgery Outperforms Laparoscopic for Rectal Cancer
Robotic surgery shows better long-term outcomes for middle and low rectal cancer compared to laparoscopic techniques. 3-year disease-free survival rate: 86.7% for robotics vs. 83.3% for laparoscopy (p=0.017). Lower 3-year locoregional recurrence (2.2% vs. 4.7%, p=0.001) and postoperative complications (14.3% vs. 19.5%, p<0.001) with robotic surgery. This suggests robotic techniques may enhance surgical decision-making and […]
Improved Prognosis for Locally Advanced Rectal Cancer Patients
A new prognostic model combines tumor regression grading and yptnm staging to better predict outcomes in locally advanced rectal cancer after neoadjuvant therapy. The novel trg-yptnm model outperformed the traditional yptnm system in both training (1,046 patients) and validation (354 patients) cohorts. Trg and yptnm are independent prognostic factors, enhancing risk stratification for surgical candidates. […]
Advancing Endoscopic Resection for Colorectal Lesions
A new saline-immersion technique shows promise for complex colorectal resections. 181 lesions treated with an en bloc approach achieved an R0 resection rate of 92.3%. Overall, 4.4% of patients experienced adverse events, with only four needing further intervention. This technique enhances the safety profile of endoscopic procedures, supporting wider use in Western surgical practice. 93.4% […]
Surgery First Improves Outcomes in Primary Intestinal Lymphoma
Surgery first significantly enhances survival and safety in primary intestinal lymphoma compared to chemotherapy first. 3-year and 5-year overall survival rates were higher in the surgery first group (p < 0.05). Patients under 60, with stage I-II disease and low international prognostic index (IPI) scores, saw even greater survival benefits (p < 0.05). You should […]
No Drains? New Option for Rectal Cancer Surgery
Microporous polysaccharide hemospheres significantly reduce complications in rectal cancer surgery without drains. Surgical complications were 12.2% in the mph group compared to 26.2% with prophylactic drains. The odds of complications in the mph group were nearly half that of the no-drain group (odds ratio: 0.54). Consider adopting mph to enhance recovery protocols and minimize postoperative […]
CRS/HIPEC Improves Survival in Low-Grade Appendiceal Carcinoma
CRS/HIPEC significantly enhances survival for select low-grade appendiceal carcinoma patients with peritoneal and parenchymal metastases. Median overall survival (OS) for low-grade mucinous and non-mucinous patients after CRS/HIPEC was not reached, compared to 50 months for surgery alone and 26 months for systemic chemotherapy (p < 0.01). In multivariable analysis, CRS/HIPEC reduced mortality risk for low-grade […]
Enhancing Outcomes in High-Risk Rectal Cancer Patients
Total neoadjuvant therapy (TNT) significantly improves response and survival in high-risk rectal cancer patients. Clinical complete response rate with TNT was 25.8%, compared to 4.0% with conventional chemoradiotherapy (p < 0.001). TNT showed superior overall survival (hazard ratio 0.48) and disease-free survival (hazard ratio 0.62) versus chemoradiotherapy. Adopting TNT can facilitate organ preservation strategies while […]
New SMA Technique Cuts Time and Blood Loss in Colon Surgery
A modified SMA approach improves outcomes for laparoscopic right colectomy in colon cancer patients. The modified SMA technique reduced operative times significantly compared to the traditional approach. It also led to lower intraoperative blood loss and fewer complications. Surgeons may want to consider using the modified SMA for safer, more efficient surgeries, especially in patients […]
Minimally invasive techniques cut mortality in early rectal cancer
Transanal endoluminal surgery (TES) shows significant advantages over endoscopic submucosal dissection (ESD) for T1 rectal cancer. 1-year mortality: 2.3% for TES vs. 10.1% for ESD; 10-year mortality: 11.6% vs. 27.1%. Hospital readmissions at 1 month: 3.4% for TES vs. 19.6% for ESD. Fewer complications with TES, including reduced procedural pain and thromboembolic events. Choose TES […]