Tech Coloproctol16 Apr 2025
A systematic review and meta-analysis revealed that circular skin closure (CSC) markedly decreases the rate of surgical site infections (SSI) following stoma closure compared to primary sutures (PS). Researchers found that only 4% of patients using CSC developed SSI, in contrast to 27% in the…
Intestine and Lower Gastrointestinal Tract15 Apr 2025
A systematic review involving 1,002 patients revealed that extraperitoneal colostomy (EPC) significantly lowers the incidence of parastomal hernia compared to transperitoneal colostomy (TPC) after laparoscopic abdominoperineal resection for rectal cancer. The EPC technique also showed reduced rates of stoma retraction, prolapse, and overall stoma-related complications.…
Eur J Surg Oncol14 Apr 2025
A systematic review and meta-analysis reveals that contact X-ray brachytherapy (CXB) provides an 82% clinical complete response rate in rectal cancer patients, presenting a compelling alternative to radical surgery. With a 14% salvage surgery rate and 81% organ preservation, CXB demonstrates long-term disease control, particularly…
Br J Surg13 Apr 2025
Broad implementation of Watch-and-Wait for rectal cancer in the Netherlands shows promising results. Among 1,080 patients, 45% achieved clinical complete response post-treatment, with a three-year organ preservation rate of 76%. The study also found a 23% incidence of local regrowth and an overall survival rate…
World J Surg13 Apr 2025
Researchers aim to assess the impact of standardized prehabilitation protocols on clinical outcomes for colorectal cancer patients in the Netherlands. By recruiting 1,070 patients, including those undergoing prehabilitation and a matched historical cohort, they will analyze postoperative complications, length of hospital stay, and readmission rates.…
Gastrointest Endosc11 Apr 2025
EUS-guided pelvic abscess drainage (EUS-PAD) using lumen-apposing metal stents demonstrates high efficacy and safety in managing complicated acute diverticulitis. In a study involving 53 patients, the procedure achieved a technical success rate of 92.5% and a clinical success rate of 88.7%. Adverse events were minimal,…
Lancet10 Apr 2025
A pragmatic trial involving 57,404 individuals revealed that faecal immunochemical test (FIT) screening is non-inferior to colonoscopy in reducing colorectal cancer mortality over 10 years. Participation rates were higher for FIT at 39.9% compared to colonoscopy's 31.8%. The colorectal cancer mortality risk was nearly identical…
Am J Gastroenterol10 Apr 2025
A nationwide study in Japan reveals that the risk of adverse events (AEs) during colorectal endoscopic submucosal dissection (ESD) escalates significantly in older adults, particularly those aged 85 and above. Among 143,925 patients, AEs were recorded at 5.3% for ages 60-64, rising to 9.2% for…
Dis Colon Rectum9 Apr 2025
A nationwide study involving 879 patients revealed that extended colectomy significantly improves overall and disease-free survival rates for individuals with ulcerative colitis-associated neoplasia compared to segmental colectomy. Specifically, five-year disease-free survival rates for total proctocolectomy and subtotal colectomy were 87.8% and 83.9%, respectively, outperforming segmental…
BMC Gastroenterol9 Apr 2025
A newly implemented mobile app for colorectal cancer (CRC) screening showed high adoption rates among healthcare professionals. With over 12,000 consultations recorded, the app facilitated appropriate recommendations, advising 50% of patients on using fecal occult blood tests instead of colonoscopies. Notably, the app supported the…