Category: Intestine and Lower Gastrointestinal Tract

Extent of Resection and Long-Term Outcomes for Appendiceal Adenocarcinoma

Mucinous and non-mucinous appendiceal adenocarcinomas exhibit differences in recurrence rates and nodal positivity. Colectomy is associated with improved disease-specific survival for non-mucinous tumors at certain stages and grades, but not for mucinous tumors. This suggests that colectomy may not be necessary for mucinous appendiceal adenocarcinoma patients. Journal Article by Tsagkalidis V, Choe JK (…) Ecker […]

Mesenteric-based Surgery for Crohn’s Disease: Addressing Anastomotic Recurrence

Mesenteric-based surgery offers insights into postoperative anastomotic recurrence in Crohn’s disease. The mesenteric pole is implicated in recurrence after resection. However, the mesentery’s role remains debated. This review explores mesenteric changes, its proposed role in disease progression, and the potential of mesenteric-based surgery in managing Crohn’s disease surgically. Review by Duan M, Coffey JC and […]

Procalcitonin >0.5 ng/ml at Admission as a Risk Stratification Tool in Acute Left-Sided Colonic Diverticulitis

Procalcitonin >0.5 ng/ml at admission indicates increased risk for complicated diverticulitis, need for surgery, and mortality. It serves as a valuable tool for severity assessment and treatment decisions. The study enrolled 503 patients, revealing procalcitonin’s independent association with complicated diverticulitis, surgery, and mortality, underscoring its clinical relevance in guiding management strategies. Journal Article by Schena […]

Minimally Invasive Surgery Outcomes for Large Colonic Adenocarcinomas

Large colonic adenocarcinomas are commonly right-sided, present at advanced stages, and have adverse pathologic features. Minimally invasive surgery is linked to better overall survival and shorter-term benefits compared to open surgery, offering significantly lower rates of mortality, positive margins, and shorter hospital stays for patients with stage I-III disease. Journal Article by Emile SH, Horesh […]

BRAF Mutations and Survival After Liver Surgery in Patients with Colorectal Liver Metastases

BRAF mutations in colorectal cancer patients with liver metastases are linked to poorer survival outcomes. However, liver resection shows a significant 56% reduction in the risk of death for patients with BRAF-mutated colorectal liver metastases. Surgical intervention offers a clear survival benefit, with a reduced hazard ratio of 0.44 favoring surgery. Review by Petrelli F, […]

Increased Long-Term Risk of Cancer in Patients with Diverticular Disease

Study findings show elevated relative risk of cancer, excluding colorectal, following diverticular disease diagnosis. There is a higher risk for lung, bronchi, trachea, and kidney cancers. The decreased risk of colorectal cancer may be due to colonoscopy with polypectomy in diverticular disease patients. Prevalence of cancer risk factors in diverticular disease patients likely contributes to […]

Minor impact of anastomotic leakage on long-term male urinary and sexual function

Anastomotic leakage after anterior resection for rectal cancer has a minor negative impact on male urinary function, leading to increased urinary incontinence rates. However, it does not significantly affect sexual function or increase risks of urinary frequency, permanent urinary catheter use, or sexual inactivity in the long term. Journal Article by Rutegård M, Jutesten H […]

Inflammatory Bowel Disease Increases Colorectal Cancer Surgery Burden

Inflammatory bowel disease negatively impacts surgery outcomes for colorectal cancer patients, leading to lower rates of surgical resection, higher postoperative complications, extended hospital stays, increased readmissions, decreased home discharges, and higher expenditures. These patients have a lower probability of achieving ideal postoperative outcomes and experience worse long-term survival after colorectal cancer resection. Journal Article by […]

Factors influencing unplanned overnight monitoring after same day discharge in colorectal surgery

Same day discharge (SDD) in colorectal surgery is feasible, but patient factors such as operative complexity and social considerations significantly influence the need for unplanned overnight monitoring. Factors like age and type of procedure impact discharge decisions, highlighting the importance of individualized patient assessment for successful implementation of SDD protocols. Review by Holtestaul T, Vu […]