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Endoscopic submucosal dissection (ESD) demonstrated superior efficacy over endoscopic mucosal resection (EMR) in treating rectal lesions involving the dentate line. ESD had higher en bloc and complete resection rates, lower recurrence rates, and higher curative rates, especially for low-risk adenocarcinomas. ESD should be considered the…
Robotic total mesorectal excisions show higher 5-year overall survival rates and comparable long-term oncological outcomes compared to laparoscopic approach for rectal cancer. Additionally, robotic surgery results in lower conversion rates, shorter hospital stays, and fewer postoperative complications. This study suggests robotic surgery as a safe…
Preoperative education significantly increases adherence to enhanced recovery program components among colorectal surgery patients, leading to improved surgical outcomes. A retrospective cohort study of 997 patients revealed higher adherence rates in those who received preoperative education, particularly in areas like fasting protocols. This study underscores…
Adjuvant chemotherapy significantly improves overall survival in rectal cancer patients who achieve a pathological complete response after neoadjuvant chemoradiotherapy and surgery. A meta-analysis of 31,558 patients showed favorable outcomes with adjuvant therapy compared to those without it. The findings support the recommendation for clinicians to…
Robotic rectal cancer surgery (rrcs) is superior to laparoscopic rectal cancer surgery (lrcs) in maintaining urinary and sexual function postoperatively, as seen in a meta-analysis of 13 studies with 1964 patients. Patients who underwent rrcs had significantly better urinary function and male/female sexual function scores…
Advancements in endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) have revolutionized the management of lower gastrointestinal malignancies. These techniques enable curative management of lesions with minimal morbidity, challenging traditional surgical approaches. The evolution from snare polypectomy to sophisticated ESD, along with technological innovations…
Study finds no significant difference in recurrence rates between endoscopic and surgical resection for high-risk T1 colon cancer. Lymphovascular invasion emerges as the sole independent risk factor for recurrence, highlighting its clinical relevance in treatment decisions. The findings suggest that both modalities can be equally…
Combining C-reactive protein-to-albumin ratio and comprehensive risk score is independently associated with better overall and recurrence-free survival in colorectal cancer patients across all disease stages. The combined score outperforms individual risk factors, offering a potent prognostic tool for patient management post-surgery, with potential implications for…
In metastatic Grade 1 gastro-entero-pancreatic neuroendocrine tumors (GEP-NETs), a higher burden of liver disease significantly reduces progression-free survival (PFS). Patients with concomitant extra-hepatic involvement have a lower overall survival (OS) rate. Liver tumor burden emerged as the sole predictor of PFS. These findings suggest a…
Osteosarcopenia, identified in 16.5% of patients, significantly increased the risk of postoperative complications after curative surgery for colorectal cancer. Patients with osteosarcopenia had lower 5-year overall survival and recurrence-free survival rates compared to those without osteosarcopenia. Multivariate analysis confirmed osteosarcopenia as an independent prognostic factor…
