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Intestine and Lower Gastrointestinal Tract

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BMC Surg26 Jun 2024

Triple-row staple technology may reduce risk of anastomotic leak

Triple-row staple technology may reduce the risk of anastomotic leak in left-sided colorectal anastomoses. After reviewing 340 relevant citations, 6 retrospective cohort studies met inclusion. Overall, 19,372 patients had anastomoses with double-row staple technology, and 2,298 patients with triple-row staple technology. Most operations were anterior…

J Gastrointest Surg26 Jun 2024

Non-Compliance with NCCN Guidelines Affects 25% of Colon Cancer Patients

Non-compliance with NCCN guidelines for colon cancer treatment affects one in four patients. Factors such as older age, female sex, black race, and tumor characteristics decrease the likelihood of guideline compliance. Conversely, higher hospital volume, specific surgical approaches, and insurance status increase compliance rates. Patient…

Intestine and Lower Gastrointestinal Tract26 Jun 2024

Conversion Surgery Reduces Mortality in Metastatic Colorectal Cancer

Conversion surgery significantly reduced mortality risk by 42% in patients with unresectable metastatic colorectal cancer treated with anti-EGFR agents and bevacizumab. Subgroup analyses showed reduced risks of mortality in patients with specific characteristics. While targeted therapy reduced mortality risk, the difference was not statistically significant…

BMC Surg26 Jun 2024

Interdisciplinary Laparoscopic Approach Improves Quality of Life in Women with ODS and POP

Interdisciplinary laparoscopic resection rectopexy combined with sacrocolpopexy is safe and effective for women with obstructive defecation syndrome (ODS) and pelvic organ prolapse (POP). Outcomes include significant improvement in ODS scores, bowel function, and incontinence. The approach restores pelvic floor anatomy in 80% of patients and…

Dis Colon Rectum25 Jun 2024

AI Imaging Diagnosis Improves Lymph Node Metastasis Detection in Low Rectal Cancer

High-precision AI imaging methods, combining super-resolution and 3D shape data, show promising outcomes for diagnosing lymph node metastasis in low rectal cancer. In a pilot study, these methods demonstrated superior sensitivity, negative predictive value, and accuracy, offering potential as a game changer in cancer diagnosis…

Surg Endosc24 Jun 2024

Frailty Index and Colonic Diverticular Surgery Outcomes

Use of the modified frailty index (mfi-11) showed a significant association between frail patients undergoing colonic diverticular disease surgery and increased postoperative mortality and morbidity. Findings reveal higher postoperative mortality, morbidity, longer hospital stays, and increased costs in frail individuals. The mfi-11 could serve as…

Intestine and Lower Gastrointestinal Tract24 Jun 2024

Cephalosporins Superior to Non-cephalosporins in Preventing SSIs in Colorectal Surgery

Meta-analysis of eight studies demonstrates that the incidence of surgical site infections (SSIs) was significantly lower in patients receiving cephalosporin antibiotics compared to non-cephalosporins after colorectal surgery (14.8% vs 25.1%). Cephalosporins may be more effective in the short term, but long-term efficacy is similar. Clinicians…

World J Surg Oncol24 Jun 2024

Prognostic Value of Examined Lymph Node Count in CRC

Higher examined lymph node (ELN) counts (≥17) in stage III colorectal cancer (CRC) patients correlate with improved long-term survival outcomes. ELN count independently predicts overall survival, cancer-specific survival, and progression-free survival. Subgroup analysis highlights benefits in patients treated with adjuvant chemotherapy with medium to large…