Study of over 570,000 patients reveals that the type of index complication in noncardiac surgeries significantly impacts patients’ outcomes. Patients with specific complications like bleeding, cardiac, or graft issues are more likely to experience secondary complications, failure to rescue, longer hospital stays, or reoperations. Tailoring quality improvement strategies to address different index complications could improve […]

Analysis of 7,474,298 patients revealed decreasing preoperative risk and unadjusted postoperative complication rates from 2005 to 2018 within ACS-NSQIP. While mortality levels remained stable, other complications saw reductions, except for cardiac issues. Hospitals in the program experienced enhanced risk-adjusted outcomes, indicating a positive trend in surgical care quality improvement. Journal Article by Stuart CM, Henderson […]

Postoperative complications in high-risk surgical populations increase mortality, disability, and costs. BIGPROMISE cohort profile discusses rationale and scope to investigate risk factors and outcomes related to postoperative complications. Over 3000 adult patients undergoing major surgery contribute data and biomarkers for analysis. With a focus on pathophysiological processes, the study aims to improve risk stratification for […]

Patients in regions with poorer food environments exhibit higher odds of late-stage gastrointestinal cancer diagnosis and worse survival rates. These disparities are pronounced across various cancer types, highlighting the need for targeted interventions to mitigate socioeconomic and dietary influences on cancer outcomes. Journal Article by Fei-Zhang DJ, Schellenberg SJ (…) Pawlik TM et 2 al. […]

Postoperative outcomes among patients treated by international medical graduate (IMG) surgeons were comparable to those by United States medical graduate (USMG) surgeons. IMG surgeons had lower rates of adverse postoperative outcomes, such as 90-day readmission and index complications. They were also more likely to care for patients with multiple comorbidities and from vulnerable communities, showcasing […]

Postoperative complications were associated with significantly worse patient-reported outcomes, including lower physical and mental health scores, higher pain interference and fatigue, and lower physical function. A substantial number of patients reported outcomes below national benchmarks, emphasizing the need for improved post-surgical care to enhance patients’ quality of life. This study highlights the critical impact of […]

Among general surgery patients, major bleeding, sepsis, and myocardial injury after non-cardiac surgery (MINS) were independently associated with 30-day mortality. These complications had the largest attributable fraction of post-operative deaths. Findings suggest the need for strategies, such as perioperative bleeding prophylaxis, to reduce mortality in this patient population. Journal Article by Park LJ, Borges FK […]

Dexmedetomidine significantly decreases postoperative acute kidney injury (AKI) incidence compared to controls (RR 0.60, 95% CI 0.45-0.78), shortening ICU and hospital stay but increasing bradycardia risk. Meta-analysis of 25 trials (n=3,997) demonstrates its efficacy in AKI prevention post-surgery, offering potential benefits in patient outcomes. Review by Zhao J, Tang MH, Shen QH and Xu DC […]

Effective management of intra-abdominal infections (IAIs) is crucial, with early diagnosis, proper source control, and timely antimicrobial therapy being key. Inappropriate antimicrobial treatment can lead to poor outcomes, including increased mortality. Optimizing antimicrobial prescriptions not only improves treatment effectiveness and patient safety but also helps minimize the risk of opportunistic infections and antimicrobial resistance. A […]

Intra-abdominal infections cause significant morbidity and mortality in hospitals. Effective management involves rapid diagnostics, timely source control, and appropriate antimicrobial therapy. Key strategies include personalized treatment plans based on infection extent, pathogens, resistance risk, and patient condition. Hemodynamic and organ support with intravenous fluids and vasopressors are essential for critically ill patients. Continuous assessment of […]