Researchers analyzed data from 1582 patients with small intestinal stromal tumors to identify risk factors for liver metastasis. They found that poor tumor grade, absence of surgery, later T-stage, and no chemotherapy were associated with an increased risk of liver metastasis. A nomogram prediction model showed good performance in predicting liver metastasis, and patients with […]
Category: Sarcoma & rare tumors
Textbook Outcome in Pancreatoduodenectomy for Nonfunctioning Pancreatic Neuroendocrine Tumors
Textbook outcome (TO) was achieved in one-third of patients after pancreatoduodenectomy (PD) for nonfunctioning pancreatic neuroendocrine tumors (NF-PANNETs). Tumor size, minimally invasive approach, and surgical volume were predictors of TO. TO was not associated with improved long-term survival, with similar rates seen in patients with and without TO. The TO rate was higher in patients […]
Radical resection favored for grade 2 rectal neuroendocrine tumors >1.5 cm
Comparing local excision and radical resection for grade 2 rectal neuroendocrine tumors showed no significant difference in survival for tumors ≤1.5 cm. However, tumors >1.5 cm had significantly lower relapse-free survival with local excision. Lymph node metastasis was present in 60% of patients who underwent radical resection. The study concluded that local excision is suitable […]
En-bloc resection of well-differentiated nonampullary duodenal neuroendocrine tumors is safe and effective
Endoscopic resection of well-differentiated nonampullary duodenal neuroendocrine tumors was safe and effective, with a high rate of en-bloc and R0 resections. Tumors located in the second part of the duodenum, ≥10mm in size, and with muscularis propria invasion were risk factors for non-curative resection. Adverse events were rare and successfully managed. Long-term outcomes showed low […]
Improvement in Clinical Outcomes and Diagnostic Accuracy with Multidisciplinary Management of Retroperitoneal Liposarcoma
Multidisciplinary team management in retroperitoneal liposarcoma treatment led to higher overall survival rates at 1, 3, and 5 years, improved diagnostic consistency, reduced perioperative mortality and postoperative complications, and enhanced disease awareness and postoperative compliance. The intervention showed significant benefits in clinical outcomes and diagnostic accuracy, highlighting the importance of multidisciplinary approaches in managing retroperitoneal […]
Identification of low-risk surgical candidates for small intestinal neuroendocrine tumors through combined imaging
A tailored diagnostic protocol using contrast-enhanced computed tomography enterography and 68 Ga dotatate PET/CT showed high sensitivity and specificity in detecting primary small intestinal neuroendocrine tumors (SI-NETs) and distal lymph node disease. The combined imaging allowed for the identification of low-risk surgical candidates with single SI-NET lesions and distal lymph node disease preoperatively, enabling potential implementation […]
Significant Survival Benefit of Multimodality Treatment in Gallbladder Neuroendocrine Neoplasms
Gallbladder neuroendocrine neoplasms (GB NENs) are predominantly represented by neuroendocrine carcinomas. Outcomes analysis of 147 patients revealed a median overall survival (OS) of 6.14 months, with significant improvement to 20.20 months for those who received multimodality treatment versus 4.00 months for those who did not. These findings highlight the efficacy of multimodality approaches in improving […]
Prone Jack-Knife Transanal Minimally Invasive Surgery: A Safe and Effective Approach for Anterior Low Rectal Gastrointestinal Stromal Tumors
Prone Jack-Knife Transanal Minimally Invasive Surgery (tamis) is a feasible and safe approach for managing subepithelial rectal lesions, specifically anterior low rectal gastrointestinal stromal tumors (gist). This surgical technique, performed with the patient in the prone jack-knife position and using transanal access, provides excellent surgical ergonomics and avoids the need for radical resection. The study […]
Racial Disparities in Surgical Treatment Offer for Neuroendocrine Neoplasms
The study investigated the factors associated with offering surgery for pancreatic and small bowel neuroendocrine neoplasms (pannen and sbnen). Analysis of the surveillance databases revealed that non-white race was associated with decreased odds of surgery offer for sbnen but not pannen. These findings highlight racial/ethnic disparities in the course of treatment, indicating that non-white patients […]
A Comparative Analysis of Surgical Techniques and Outcomes for Internal Hemipelvectomy
Implementing advancements in technology and surgical technique for internal hemipelvectomy procedures can significantly impact patient outcomes. A retrospective study conducted at a single institution examined the experiences of surgeons and the utilization of new techniques and technologies over a 26-year period. The study found that the use of three-dimensional (3D) computer navigation and customized 3D-printed […]