Multidisciplinary team management in retroperitoneal liposarcoma treatment led to higher overall survival rates at 1, 3, and 5 years, improved diagnostic consistency, reduced perioperative mortality and postoperative complications, and enhanced disease awareness and postoperative compliance. The intervention showed significant benefits in clinical outcomes and diagnostic accuracy, highlighting the importance of multidisciplinary approaches in managing retroperitoneal […]
Category: Sarcoma & rare tumors
Identification of low-risk surgical candidates for small intestinal neuroendocrine tumors through combined imaging
A tailored diagnostic protocol using contrast-enhanced computed tomography enterography and 68 Ga dotatate PET/CT showed high sensitivity and specificity in detecting primary small intestinal neuroendocrine tumors (SI-NETs) and distal lymph node disease. The combined imaging allowed for the identification of low-risk surgical candidates with single SI-NET lesions and distal lymph node disease preoperatively, enabling potential implementation […]
Significant Survival Benefit of Multimodality Treatment in Gallbladder Neuroendocrine Neoplasms
Gallbladder neuroendocrine neoplasms (GB NENs) are predominantly represented by neuroendocrine carcinomas. Outcomes analysis of 147 patients revealed a median overall survival (OS) of 6.14 months, with significant improvement to 20.20 months for those who received multimodality treatment versus 4.00 months for those who did not. These findings highlight the efficacy of multimodality approaches in improving […]
Prone Jack-Knife Transanal Minimally Invasive Surgery: A Safe and Effective Approach for Anterior Low Rectal Gastrointestinal Stromal Tumors
Prone Jack-Knife Transanal Minimally Invasive Surgery (tamis) is a feasible and safe approach for managing subepithelial rectal lesions, specifically anterior low rectal gastrointestinal stromal tumors (gist). This surgical technique, performed with the patient in the prone jack-knife position and using transanal access, provides excellent surgical ergonomics and avoids the need for radical resection. The study […]
Racial Disparities in Surgical Treatment Offer for Neuroendocrine Neoplasms
The study investigated the factors associated with offering surgery for pancreatic and small bowel neuroendocrine neoplasms (pannen and sbnen). Analysis of the surveillance databases revealed that non-white race was associated with decreased odds of surgery offer for sbnen but not pannen. These findings highlight racial/ethnic disparities in the course of treatment, indicating that non-white patients […]
A Comparative Analysis of Surgical Techniques and Outcomes for Internal Hemipelvectomy
Implementing advancements in technology and surgical technique for internal hemipelvectomy procedures can significantly impact patient outcomes. A retrospective study conducted at a single institution examined the experiences of surgeons and the utilization of new techniques and technologies over a 26-year period. The study found that the use of three-dimensional (3D) computer navigation and customized 3D-printed […]
Gad2 immunohistochemistry is a highly specific diagnostic tool for identifying pancreatic origin in neuroendocrine neoplasms
Researchers analyzed a large number of tissue samples and found that gad2 immunohistochemistry is a highly specific diagnostic marker for neuroendocrine neoplasms of the pancreas. The expression of gad2 was only observed in a few normal cell types, making it a potential diagnostic tool. It was found to be most commonly seen in neuroendocrine carcinomas […]
Portal Vein Resection in Pancreatic Neuroendocrine Neoplasms
Portal vein resection in surgery for pancreatic neuroendocrine neoplasms was analyzed in this study. Among 666 patients, 8% underwent portal vein resection. Postoperative complications were comparable to standard resection, with a low 90-day mortality rate. Radical resection resulted in excellent 5-year overall and disease-specific survival rates. This study provides valuable data on the perioperative and […]
Nomogram Combined Treatment Data is More Effective than AJCC Staging System for Predicting Overall Survival in GEP-NETs
Researchers conducted a study to develop and validate a nomogram for predicting overall survival (OS) in patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs). Using data from the SEER registry, they identified key prognostic factors and compared the nomogram’s performance to the AJCC staging system. The results showed that the nomogram, which combined treatment data, had a […]
Netosis in Surgery: Implications, Impact, and Potential Treatments for Surgeons
Netosis, the formation of neutrophil extracellular traps (NETs), is a novel function of neutrophils. These NETs play a crucial role in trapping microorganisms and preventing their spread throughout the body. However, they can also lead to tissue damage and contribute to various diseases like gallstone formation, acute pancreatitis, impaired wound healing, intravascular coagulation, cancer growth, […]