A study involving 193 colon cancer patients revealed that only those with persistent postoperative inflammation faced a heightened risk of muscle wasting and poor prognosis. Groups characterized by consistent high inflammation demonstrated significant increases in muscle loss compared to those with low inflammation. Elevated inflammation was identified as an independent risk factor for postoperative sarcopenia, […]
Category: General Surgery
Indocyanine green enhances tumor identification during liver surgery
Indocyanine green (ICG) significantly boosts procedural adjustments and tumor identification in minimally invasive liver surgery, according to findings involving 72 patients. Intraoperative ICG visualization proved “helpful” for 88% of surgeons, with meaningful differences in tumor positivity (12.2% in the ICG group vs. none in the control). This led to higher rates of frozen section analysis […]
Colectomy rates for ulcerative colitis decrease in Brazil.
A significant rise in ulcerative colitis prevalence was noted in Brazil, escalating from 17.31 to 84.23 per 100,000 between 2012 and 2022, with an annual increase of 15%. Conversely, while colectomy procedures accounted for 69.4% of surgeries, the percentage relative to total UC patients decreased to 0.7%, reflecting an 11.8% decline. Additionally, hospitalization rates dropped […]
Laparoscopic cholecystectomy outperforms medication for gallstone treatment
Laparoscopic cholecystectomy shows superior clinical efficacy compared to non-invasive gallstone dissolution, enhancing patient quality of life. In a study of 86 cholelithiasis patients, surgical intervention resulted in a higher effective rate, faster symptom relief, and shorter hospital stays, despite increased costs. Additionally, the surgical group experienced fewer complications and lower recurrence rates. Improvements in SF-36 […]
Anemia and ICG-FI Use Increase Risk of Leakage
A study of 304 rectal cancer surgery patients revealed that moderate or severe anemia and non-use of indocyanine green fluorescence imaging (ICG-FI) are significant independent risk factors for anastomotic leakage. Preoperative anemia correction and routine ICG-FI application may reduce this risk. The analysis calculated an odds ratio of 9.94 for anemia and 10.40 for ICG-FI […]
Preoperative CEA levels can predict survival in rectal cancer.
A new study identifies a preoperative carcinoembryonic antigen (CEA) cutoff of 2.8 ng/ml as significant for predicting 5-year survival in rectal cancer patients. Analysis of 316 individuals revealed that higher CEA levels correlate with poor overall survival. The presence of lymphovascular and perineural invasions also emerged as critical prognostic indicators, with patients achieving a pathologic […]
Radiographic response depth predicts survival in HCC patients.
Improved outcomes for patients with initially unresectable hepatocellular carcinoma are linked to the depth of radiographic response after systemic therapy prior to hepatectomy. In a study of 81 patients, radiographic response emerged as an independent prognostic factor for both recurrence-free and overall survival. Notably, achieving a radiographic response greater than 40% or 50% significantly correlated […]
FOLFIRINOX shows superior outcomes for locally advanced pancreatic cancer
Neoadjuvant therapy (NAT) with FOLFIRINOX significantly enhances resectability and overall survival (OS) in patients with locally advanced pancreatic cancer (LAPC). This umbrella review of nine systematic reviews highlights that FOLFIRINOX leads to higher R0 resection rates compared to gemcitabine/nab-paclitaxel, with improved OS. Furthermore, surgical resection post-NAT provides better survival outcomes than induction therapy alone. Cost-effectiveness […]
A new nomogram enhances prediction of postpancreatectomy hemorrhage
A novel nomogram has been developed to accurately predict late extraluminal postpancreatectomy hemorrhage (lepph) in patients with postoperative pancreatic fistula following pancreaticoduodenectomy. Utilizing a combination of key independent risk factors such as dorsal fluid accumulation and positive cultures in drainage fluid, the model demonstrated high predictive accuracy with c-index values of 0.932, 0.924, and 0.954 […]
A validated risk score predicts 90-day mortality after liver resection
A novel preoperative risk score predicts 90-day mortality after major liver resection, identifying five key risk factors: age ≥ 65 years, type 2 diabetes, a diagnosis of primary liver cancer, ASA ≥3, and extended hemihepatectomy. In a cohort of 513 patients, the 90-day mortality rate was 10.8%, with predicted rates of 3.5% for low risk, […]