Neoadjuvant Immunotherapy Changes Localized Rectal Cancer Management
Neoadjuvant immunotherapy shows promise for rectal cancer, challenging traditional surgical approaches.
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Best Papers in General Surgery
The five that matter, every day.
Neoadjuvant immunotherapy shows promise for rectal cancer, challenging traditional surgical approaches.
ECVF from contrast-enhanced CT can predict postoperative pancreatic fistula risk.
A retrospective analysis of 218 patients reveals that refined resection margin classifications significantly impact recurrence patterns in hilar cholangiocarcinoma. Adjuvant radiotherapy sharply reduces local recurrence rates, particularly in patients with narrow-clear and invasive margins. Notably, no recurrences were observed in patients with wide-clear, narrow-clear, or…
Chewing gum significantly reduces time to first postoperative flatus and bowel movement by over 12 and 19 hours, respectively, while cutting hospital stays by nearly a day. It also lowers the incidence of bowel obstruction. Involving nearly 5,000 patients across 35 trials, this systematic review…
Anastomotic leakage (AL) poses a significant threat to recovery in gastrointestinal surgeries. Key risk factors include ASA scores of 3-4, male gender, diabetes, hypertension, and chronic kidney disease. Preoperative mechanical bowel preparation with oral antibiotics can markedly decrease AL incidence. Additionally, intraoperative techniques—like collagen sealants…
A novel random survival forest model effectively stratifies hepatocellular carcinoma patients into high- and low-risk groups for recurrence and mortality post-surgery. Utilizing critical clinicopathological features and molecular markers, the model demonstrates significant differences in 5-year recurrence and death probabilities. For instance, in the training cohort,…
A new composite criterion, coined the textbook outcome (TO), evaluates laparoscopic common bile duct exploration for choledocholithiasis. Analyzing 225 patients, 74.2% achieved TO, defined by key perioperative benchmarks such as no residual stones and no severe complications. High ASA scores emerged as a critical risk…
Robot-assisted surgery (RAS) adoption in the Netherlands skyrocketed over the last decade, jumping from 1% to 33% for pancreatic resections. The trend reflects broader integration across gastrointestinal and thoracic surgeries, with RAS now utilized in 20% of all procedures. Notably, rectal surgeries experienced the greatest…
Esophageal corrosive injuries, predominantly from intentional alkaline ingestion, present serious medical hurdles, with a mortality rate of 6.2% and stricture formation occurring in 24.7% of cases. A comprehensive meta-analysis of 44 studies highlighted that endoscopy demonstrates higher sensitivity (82.4%) than computed tomography (63.8%) for predicting…
In small bowel obstruction cases, younger patients with fewer comorbidities are more likely to undergo laparoscopic surgery, which is linked to fewer complications and lower mortality compared to open surgery. Etiology plays a key role; adhesive obstructions favor laparoscopy while hernias prompt open procedures. Notable…