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Best Papers in General Surgery
The five that matter, every day.
Enhancing the fibrinogen-to-erythrocyte suspension ratio could significantly reduce mortality and improve functional outcomes in major perioperative bleeding scenarios. The ADEFES study focuses on patients undergoing surgeries that entail substantial blood loss, evaluating the relationship between fibrinogen supplementation and critical recovery metrics. By scrutinizing the effect…
Biliary strictures, often resulting from various causes, disrupt bile flow and lead to significant complications. Traditional surgical methods are now complemented by advanced strategies, including molecular therapies targeting fibrosis pathways, gene-editing technologies, and tissue-engineered scaffolds. These approaches promise improved, safer treatment options tailored for precision…
Minimally invasive liver surgeries demonstrate significant benefits over open resections, especially in advanced cases. Among 686 patients, robotic-assisted procedures reduced major complications to 8%, compared to 17% for laparoscopic and 23% for open surgeries. Both laparoscopic and robotic approaches showed lower blood loss and shorter…
Myopenia significantly reduces both overall and disease-free survival in gastric cancer patients post-radical gastrectomy. In a cohort of 943 patients, those with myopenia had a five-year overall survival rate of 45.5%, compared to 69.3% for those without. A new nomogram integrating myopenia risk assessments outperformed…
A machine learning model accurately predicts optimal treatment choices for hepatocellular carcinoma, comparing liver transplantation to surgical resection. The model stratifies patients into high- and low-risk groups, estimating potential survival improvements from tailored decisions. In a nationwide study of over 4,500 patients, machine learning outperformed…
Implementing the Enhanced Recovery After Surgery (ERAS) protocol significantly enhances perioperative outcomes in robotic hepatectomy. A study of 544 patients revealed reduced estimated blood loss—from 214.7 to 141.7 mL—and a drop in 90-day readmission rates from 22.6% to 13.4%. Notably, post-ERAS patients presented higher rates…
A retrospective analysis of 479 general surgery patients revealed that 12.5% developed surgical site infections (SSIs). Independent risk factors for SSIs included elevated body mass index, diabetes mellitus, emergency surgeries, prolonged operative times, conventional operating room settings, changes in surgical personnel, and poor adherence to…
Endosonography-guided coloenterostomy (CE) significantly enhances outcomes for patients with small-bowel ileus due to peritoneal carcinomatosis. In a cohort of 17 patients, CE achieved a 94% technical success rate, with most experiencing symptom relief and improved quality of life. Notably, overall survival spanned 86 days compared…
Patients with resected esophageal cancer receiving 41.4 Gy of neoadjuvant radiation saw improved overall survival compared to those treated with higher doses of 50-50.4 Gy. At a median follow-up of 61.6 months, median survival was 59.9 months for the lower dose vs. 45.5 months for…
A rising proportion of geriatric patients in trauma centers significantly influences outcomes. While mortality for geriatric patients improves with increased numbers, a threshold of 65% total volume results in a plateau. Alarmingly, when the geriatric share exceeds 61%, mortality rates among nongeriatric adults start to…
