Newsletter
Best Papers in General Surgery
The five that matter, every day.
An artificial intelligence model developed for marking detection and incision guidance during esophageal endoscopic submucosal dissection (ESD) demonstrated promising performance. Compared to junior endoscopists, the AI achieved a notable accuracy of 63.21%, precision rates of up to 85.76%, and an average distance error of 0.096,…
A scoping review of 26 studies reveals digital and telemedicine tools significantly improve postoperative pain management at home. These technologies, including mobile apps and wearable sensors, facilitate patient monitoring and communication with healthcare professionals, leading to better pain control, reduced opioid use, and high patient…
A meta-analysis of high-quality trials shows immunotherapy-based neoadjuvant regimens, particularly combining immunotherapy with chemotherapy and targeted therapy, significantly improve pathological complete response (PCR) rates and overall survival in locally advanced gastric cancer. The neoadjuvant immunotherapy plus chemotherapy (NICT) and NICT plus targeted therapy (NICTT) groups…
A systematic review revealed that endoscopic retrograde cholangiopancreatography (ERCP) achieves an impressive 89% success rate in treating traumatic pancreatic injuries (TPI). The procedure notably enhanced pancreatic duct integrity and led to lower complication rates (4-17%), primarily pancreatitis and bleeding. Mortality remained low at 3-5%, and…
In a comprehensive study of 5,221 adults with obesity and chronic kidney disease (CKD), bariatric metabolic surgery (BMS) demonstrated a significantly reduced risk of major adverse cardiovascular events, major adverse kidney events, and all-cause mortality over five years. The protective effects of BMS were consistent…
A review highlighted significant advancements in third-space endoscopy techniques for gastrointestinal tumors. Submucosal tunneling endoscopic resection (STER) was found to be safe and effective, achieving high en bloc resection rates and reduced recovery times. Tunneling endoscopic submucosal dissection (ESD) variants also enhance outcomes for early…
The implementation of an artificial intelligence (AI) lesion-labeling system significantly improved the complete resection rate during endoscopic submucosal dissection (ESD) in low-volume centers. In a study involving 174 patients, 90% achieved negative lateral margins, while the en bloc resection rate stood at 98.5%. Comparatively, no…
A recent retrospective study involving 1,011 patients identified critical size thresholds for rectal neuroendocrine neoplasms (NENs). For grade 1 tumors, a 0.7 cm cut-off showed 100% sensitivity and 79% specificity, indicating minimal recurrence risk. Conversely, grade 1 tumors with lymphovascular invasion necessitated a 1.5 cm…
In a comprehensive analysis of nearly 32,000 appendicitis cases in Germany, laparoscopic appendectomy emerged as the preferred surgical approach, conducted in 97% of cases by 2022. Complicated appendicitis was observed in 27.4% of patients, with variations in severity noted. Women showed a decreased likelihood of…
Carboxypeptidase Z (CPZ) emerges as a promising diagnostic biomarker for hepatocellular carcinoma (HCC), showing a remarkable 90.8% positive expression rate in a study of tumor tissues. In combination with other markers, CPZ achieved sensitivities up to 79.2% and specificities near 100%. Notably, it outperformed other…
