Newsletter
Best Papers in General Surgery
The five that matter, every day.
The study reveals that neoadjuvant immunochemotherapy significantly enhances long-term survival for patients with locally advanced esophageal squamous carcinoma, particularly those with stage III disease or suspected lymph node involvement. An analysis of 397 patients showed that while pathologic complete response rates were similar between immunochemotherapy…
The study identifies significant clinicopathological differences between esophageal gastrointestinal stromal tumors (e-gist) and gastric gastrointestinal stromal tumors (g-gist), noting e-gist's stronger male predominance, older median age, and increased tumor size and ulceration. Remarkably, endoscopic resection (ER) is found to be comparably effective to surgical resection…
Analysis of 208 patients post-curative hepatectomy for hepatocellular carcinoma revealed that a low liver-to-spleen ratio (LSR) is a strong predictor of intrahepatic recurrence. Specifically, 53% experienced recurrence, with significantly higher rates in those with low LSR values (
Dynamic changes in plasma endothelial microparticles (EMP) and soluble thrombomodulin (STM) levels significantly correlate with prognosis in severe acute pancreatitis (SAP). In a study of 128 SAP patients, higher EMP and STM levels were linked to increased mortality rates. Combined detection had a notable sensitivity…
A prospective randomized trial involving 110 patients revealed that modified partial stapled hemorrhoidopexy (mpsh) significantly reduced average and peak postoperative pain scores compared to conventional hemorrhoidectomy (ch). Patients in the mpsh group reported shorter laxative usage and earlier return to work, alongside higher satisfaction levels…
New guidelines emphasize the ongoing colorectal cancer risk in inflammatory bowel disease (IBD) patients despite improved therapies. Developed by UK stakeholders, the guidelines present 73 statements focusing on factors including surveillance intervals, service organization, and the importance of patient collaboration. Key areas include dysplasia management,…
A novel machine learning model demonstrates the potential to predict anastomotic strictures in patients following esophageal cancer surgery. Analyzing data from 1,549 patients, the gradient boosting machine achieved an area under the curve (AUC) of 0.886 in the training set and 0.872 in the validation…
A deep learning computer vision model demonstrated precise real-time identification of the left ureter during laparoscopic sigmoidectomy, achieving a mean average precision of 0.92. Key evaluation metrics, including precision, recall, and dice coefficient, reached impressive values of 0.94, 0.88, and 0.90, respectively. Operating at 32…
A cohort study of 99 patients in Switzerland evaluated refluxstop surgery's efficacy for treating gastroesophageal reflux disease (GERD) in those with small and large hiatal hernias (HH). The study reported no significant differences in adverse events between groups. Notable improvements in GERD-HRQL scores were found:…
A randomized controlled trial intends to evaluate the non-inferiority of laparoscopic distal gastrectomy (LDG) versus open distal gastrectomy (ODG) in treating clinically resectable T4A gastric cancer. With 240 participants, the trial will assess 3-year disease-free survival alongside secondary outcomes such as morbidity, mortality, recovery, and…
