A new machine learning model successfully predicted early extrahepatic recurrence (EEHR) following curative resection of colorectal liver metastases (CRLM). Among 1,410 patients, 131 (9.3%) experienced EEHR, with median overall survival significantly lower for affected patients (35.4 months) versus those without (120.5 months, p < 0.001). The model achieved a c-index of 0.77, highlighting primary tumor […]
Category: General Surgery
Decreased HVPG Post-Surgery Linked to Improved Outcomes
Laparoscopic splenectomy plus esophagogastric devascularization significantly reduced hepatic venous pressure gradient (HVPG) in patients with portal hypertension, with 66% showing a decrease. Notably, those exhibiting a postoperative HVPG reduction greater than 20% demonstrated improved recurrent hemorrhage-free survival rates compared to others. Baseline HVPG and preoperative Child-Turcotte-Pugh class B were found to correlate with decreased HVPG […]
Combined radiomics and body analysis enhance predictive accuracy for pancreatic surgery complications
A new model integrating radiomics, pancreatic duct diameter, and body composition analysis effectively predicts clinically relevant postoperative pancreatic fistula in patients undergoing pancreaticoduodenectomy. This combined approach achieved an area under the ROC curve of 0.839, outperforming existing models. Internal validation through 1,000 bootstrap resamples demonstrated the model’s reliability, culminating in the development of a web-based […]
New tool effectively identifies non-technical errors in surgery
A novel tool, SICNESS, has been developed to identify and categorize non-technical errors linked to surgical mortality. Validated through a two-pilot approach using 844 mortality cases from Australia and New Zealand, the tool demonstrated high inter-rater reliability, particularly in leadership and decision-making aspects. Its systematic application can help to retrospectively pinpoint these errors, enhancing surgical […]
Intraoperative administration of indocyanine green enhances visualization
The study compared intraoperative (IS) and preoperative (PS) indocyanine green administration for near-infrared cholangiography during laparoscopic cholecystectomy. While both methods yielded similar signal-to-background ratios, IS significantly lowered liver fluorescence intensity and achieved higher visualization scores for common hepatic ducts. Furthermore, IS facilitated a quicker critical view of safety, taking an average of 9.4 minutes versus […]
Predictive model for pathologic complete response in esophageal cancer
A new predictive model, combining small ribonucleic acids (srnas) and clinical factors, shows promise in forecasting pathologic complete response (pcr) in esophageal squamous cell carcinoma post-neoadjuvant chemoradiotherapy. Among 99 patients, significant predictors included isomirs of let-7b and mir-93, plus specific clinical indicators. The model achieved an area under the curve of 0.84, suggesting its potential […]
Laparoscopic cholecystectomy is optimal for pregnant patients with gallbladder disease
In a systematic review of 63,523 pregnant women, laparoscopic cholecystectomy (LC) emerged as the most favorable treatment for gallbladder disease. It significantly reduced risks of preterm delivery (RR: 0.23), fetal complications (RR: 0.42), and maternal complications (RR: 0.44) compared to open cholecystectomy. While cholecystectomy is safe in any trimester, the third trimester poses heightened maternal […]
A nomogram predicts postoperative biliary fistula after pancreaticoduodenectomy.
A novel nomogram has been developed to predict postoperative biliary fistula (PBF) risk after pancreaticoduodenectomy. Analyzing data from 196 patients, researchers identified diabetes, low albumin, postoperative gastroparesis, abdominal bleeding, abdominal infection, and pancreatic fistula as independent risk factors. The model demonstrated good discriminative ability with an AUC of 0.807 in the training set and 0.782 […]
Telemedicine is favored by older cancer patients for consultations
A significant majority (77%) of older cancer patients opted for telemedicine consultations over in-person visits at the Cancer and Aging Interdisciplinary Team clinic. Factors influencing in-person visit choices included older age, lower educational status, living in New York City, cognitive impairments, performance measure challenges, and social support issues. The findings highlight the potential of telemedicine […]
Nomogram effectively predicts severe complications post-surgery after COVID-19
A novel nomogram crafted to forecast severe postoperative complications in elective hepato-pancreato-biliary surgery following COVID-19 breakthrough infections demonstrated high accuracy. The model utilized data from 2,636 patients and identified significant predictors, including timing of surgery relative to the infection and vaccination status. With an area under the curve (AUC) ranging from 0.841 to 0.919 across […]