Newsletter
Best Papers in General Surgery
The five that matter, every day.
A systematic review and meta-analysis, analyzing 1,236,694 patients, revealed that females undergoing groin hernia repair suffer higher rates of recurrence (1.28), chronic pain (1.52), and surgical site infections (1.46) compared to males. Additionally, women are less likely to opt for minimally invasive surgery, exhibiting a…
A novel nomogram has been developed to predict postoperative survival in gallbladder cancer patients, incorporating eight critical factors including TNM stage and serum biomarkers. Performance metrics demonstrated consistent time-dependent concordance indices exceeding 0.70 and area under the curve surpassing 75% for 1-, 3-, and 5-year…
A comparison of laparoscopic hepatectomy (LH) and radiofrequency ablation (RFA) revealed that LH provides significantly better overall survival (OS) and disease-specific survival (DSS) for small hepatocellular carcinoma patients. In matched cohorts, 1, 3, and 5-year OS and DSS rates favored LH over RFA. For tumors…
A new simulator for transabdominal preperitoneal laparoscopic inguinal hernia repair has been validated. This model, featuring an innovative exchangeable peritoneum, was highly rated by 24 surgeons for its realistic tactile feedback and anatomical fidelity. Performance evaluations revealed that surgical experts outperformed residents, achieving higher scores…
Analysis of 10,977 patients with gastric adenocarcinoma and liver-only metastases revealed that those undergoing primary tumor resection combined with liver metastasectomy experienced significantly longer median overall survival (18.6 months) compared to non-surgical treatment (6.5 months). The study indicates that surgical resection, especially in highly selected…
A multicenter study involving 233 early-stage hepatocellular carcinoma patients revealed that microvascular invasion (MVI) grading significantly affects long-term outcomes post-laparoscopic liver resection. Specifically, median overall survival (OS) was 84.9 months for M0, 40.1 months for M1, and 25.2 months for M2. Likewise, recurrence-free survival (RFS)…
Treatment trends for locally advanced pancreatic cancer reveal that 67.67% of patients received primarily chemotherapy, with notable improvement in surgical resection rates over time. However, 41.19% also received radiation, yet many patients went untreated or did not receive guideline-recommended treatment (GRT). Socioeconomic factors like race,…
In a study involving 130 patients with unresectable colorectal cancer liver metastases, the use of contrast-enhanced intraoperative ultrasound (ce-ious) significantly improved hepatic recurrence-free survival rates compared to standard intraoperative ultrasound alone. Specifically, the ce-ious group demonstrated a lower recurrence rate (hazard ratio 0.55), especially in…
Day-case laparoscopic cholecystectomy (DCLC) is proven safe and effective for treating symptomatic gallstones, offering benefits like shorter hospital stays and improved patient satisfaction. Key findings indicate that unexpected admissions arise mainly from postoperative nausea, vomiting, and pain, while anesthesia pathways enhance day-case rates. Importantly, complication…
A comprehensive analysis of 953,612 cancer surgery patients reveals neoadjuvant immunotherapy is not significantly linked to major postoperative morbidity. The study, which evaluated cases across multiple cancer types, found a pooled odds ratio of 0.98, indicating no increased risk. Specifically, adjusted odds ratios varied by…
