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Best Papers in General Surgery
The five that matter, every day.
A cohort study involving 60 gastric cancer patients revealed that postoperative insulin resistance significantly worsens short-term recovery after radical gastrectomy. Key findings indicated increased insulin resistance and inflammation, along with decreased nutritional markers. The gut microbiome showed notable changes, including reduced bifidobacterium and butyrate levels.…
A comprehensive analysis of over 1.1 million physicians reveals only 16.7% of surgeons are female, highlighting significant ongoing gender disparities in surgery. While there is a gradual increase in female representation, specialty-specific trends show that women are less likely to enter cardiac surgery compared to…
GAME-SCORE demonstrates predictive value for pathological and radiological responses to neoadjuvant chemotherapy in colorectal liver metastases. High-risk GAME-SCORE patients exhibited significantly lower pathological response rates (82.6%) and increased radiological progression (10%) compared to low (3.8%) and moderate (3.5%) risk groups. Furthermore, multivariable analysis identified high-risk…
A study analyzed 682 patients with locally advanced rectal cancer, revealing that 6.9% experienced local recurrence post-neoadjuvant chemoradiotherapy and total mesorectal excision. Key risk factors identified included positive circumferential resection margin, venous invasion, and perineural invasion. Among those with recurrence, 53.2% were resectable, and 65.2%…
In a study of 2,180 patients who underwent major hepatobiliary and pancreatic surgery, 8.4% experienced moderate-to-severe pain within 24 hours post-operation. Key independent risk factors identified include younger age, lower body mass index, open surgical procedures, and the use of sufentanil for analgesia. Additionally, inadequate…
In a study involving 192 patients with combined hepatocellular-cholangiocarcinoma, tumor burden score (TBS) outperformed standard primary liver cancer staging in predicting post-surgical prognosis. Stratified into low, medium, and high TBS, patient outcomes declined as TBS increased. TBS proved to be an independent prognostic factor across…
A systematic review highlights the urgent need for reliable parameters that indicate futile resuscitation among severely bleeding trauma patients. By examining existing literature, researchers propose a clear roadmap to guide clinicians in recognizing when massive transfusions may be ineffective. This approach aims to enhance blood…
The C-reactive protein-albumin-lymphocyte (CALLY) index effectively predicts postoperative complications for patients with obstructive colorectal cancer undergoing colonic stenting. In a study of 263 patients, those with a low CALLY index experienced significantly higher blood loss, poorer performance status, and increased complications compared to those with…
A study involving 726 patients with upper gastrointestinal bleeding (UGIB) revealed that a high neutrophil-lymphocyte ratio (NLR) on admission significantly predicts in-hospital mortality risk. Researchers found that while 6% of patients died, 23.9% required endoscopic intervention, and 46.4% needed blood transfusion. The integration of NLR…
An innovative eight-zone laparoscopic dissection strategy significantly enhances postoperative specimen integrity and reduces nerve injury risk compared to traditional techniques in rectal cancer surgery. Among 218 patients analyzed, those undergoing the eight-zone approach demonstrated an 88.1% integrity rate in surgical specimens and improved preservation of…
