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General Surgery

Best Papers in General Surgery

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Ann Surg Oncol6 Aug 2024

Total neoadjuvant therapy shows promising survival in gastric cancer.

A study involving 203 gastric cancer patients revealed that total neoadjuvant therapy (TNT) resulted in a 5-year overall survival (OS) rate of 65.2% and a disease-specific survival (DSS) rate of 70.8%. Notably, patients achieving pathologic complete response (PCR) had significantly better outcomes, with 5-year OS…

BMC Surg6 Aug 2024

Early CT scans reduce hospital stays and mortality post-pancreatectomy

Early postoperative CT imaging after pancreatectomy significantly improved patient outcomes. Among 370 patients studied, those receiving early scans had shorter hospital stays (17.05 days vs. 22.82 days, p = .0008) and lower mortality rates (0% vs. 11%, p = .02). Early imaging also emerged as…

Surg Endosc6 Aug 2024

Reduced-port robotic pancreaticoduodenectomy proves safe and effective

A unique single-site plus-two ports technique for reduced-port robotic pancreaticoduodenectomy (rprpd) was reviewed in fifty patients, demonstrating safety and feasibility. The median operative time was 351 minutes, with an estimated blood loss of 80 ml. All procedures were completed without conversion to open surgery, and…

Appendix, Gallbladder and Surgical Emergencies6 Aug 2024

CHAMPS Score Outperforms Existing Tools in Predicting Mortality

The CHAMPS score proved highly effective in predicting mortality in patients with non-variceal upper gastrointestinal bleeding, showing an area under the receiver operating characteristic curve (AUROC) of 0.89. It significantly outperformed the Glasgow-Blatchford score (0.72) and AIM65 score (0.71). In low-risk categories, mortality and rebleeding…

J Surg Res5 Aug 2024

Early detection of anastomotic leaks enhances patient outcomes.

A comprehensive analysis determined that C-reactive protein (CRP) and procalcitonin (PCT) are effective in early detection of anastomotic leaks (AL) after colorectal surgery. Additionally, computed tomography (CT) imaging proves valuable in identifying various signs of leaks, such as fluid collection and abscess formation. By integrating…

Eur J Surg Oncol5 Aug 2024

Robotic surgery reduces risk of positive circumferential resection margins.

This systematic review and meta-analysis of 18 studies shows that robotic surgery (rs) significantly decreases the risk of circumferential resection margin (crm) positivity in rectal cancer patients undergoing mesorectal excision, with a relative risk of 0.82 (95% CI, 0.73-0.92; p=0.001). The combined data from 4…

HPB (Oxford)5 Aug 2024

Liver venous deprivation enhances surgery outcomes over portal vein embolization

In a meta-analysis involving 588 patients, liver venous deprivation (LVD) improved liver resection rates (OR, 1.89), accelerated liver growth rates, and shortened time to surgery compared to portal vein embolization (PVE). Notably, LVD resulted in lower post-hepatectomy liver failure (OR, 0.45) without increasing complications or…

Int J Surg5 Aug 2024

Imaging model improves risk stratification for HCC treatment

An imaging-derived biomarker effectively stratified mvi-positive HCC patients for adjuvant hepatic arterial infusion chemotherapy (HAIC). In a study of 470 patients, key imaging features distinguished prognostic subgroups, leading to significantly different recurrence-free survival rates (RFS) (median RFS, 6.00 vs. 66.00 months, p

Upper Gastrointestinal Tract5 Aug 2024

Prognostic models enhance survival predictions for gastric carcinoma

Development and validation of prognostic models for gastric carcinoma were achieved using data from 1,650 patients post-gastrectomy. The nomogram for node-negative lymphatic metastasis (c-index 0.719) and node-positive metastasis (c-index 0.674) outperformed the AJCC 8th edition TNM staging. Key variables included age, tumor stage, and maximum…