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Best Papers in General Surgery
The five that matter, every day.
A preoperative risk model developed by clinicians identified criteria to predict futile up-front pancreatectomy in patients with anatomically resectable pancreatic cancer. Among 1,426 patients, the rate of futile pancreatectomy was 18.9%. Clinicians identified four specific tumor size and cancer antigen (CA 19.9) criteria that maintained…
A pilot study involving 27 participants demonstrates that duodeno-ileal diversion using the sutureless neodymium anastomosis procedure (SNAP) is both technically feasible and relatively safe. Patients achieved progressive, clinically meaningful weight loss within 9 months post-procedure, with all presenting widely patent anastomoses at the 3-month mark.…
In a study of 2368 patients undergoing minimally invasive colorectal cancer surgery, prolonged postoperative ileus (PPOI) occurred in 9.5% of cases. Six independent risk factors were identified for PPOI: advanced age, male sex, comorbidity index ≥6, preoperative sarcopenia, prognostic nutritional index, and intraoperative fluid overload.…
Laparoscopic approaches to inguinal hernia repair significantly reduce chronic postoperative pain compared to the Lichtenstein technique. A meta-analysis of 13 studies revealed a relative risk of 0.49 (95% CI: 0.32, 0.75) for lower inguinodynia incidence in patients undergoing laparoscopic transabdominal preperitoneal or total extraperitoneal repairs.…
Findings reveal the albumin-lymphocyte-globulin-C-reactive protein (ALGC) index as a significant prognostic biomarker for hepatocellular carcinoma (HCC) after hepatectomy. In a cohort of 178 patients, a low ALGC index (
A Blue Ribbon Committee II has identified key challenges in surgical education and proposed recommendations to improve medical student training. The subcommittee conducted a comprehensive literature review to inform its strategies, which address recruitment, surgical engagement, and the transition from undergraduate to graduate medical education.…
A consensus was achieved among 89 international metabolic and bariatric surgeons on 29 of 30 statements regarding the prerequisites for practicing metabolic and bariatric surgery (MBS). Key criteria include holding a general surgery degree, completing a dedicated fellowship, and proficiency in managing postoperative complications. The…
A systematic review covering 3,610 patients undergoing distal pancreatectomy reveals that a no-drainage approach significantly reduces complications. The odds of postoperative pancreatic fistula decreased to 0.38, while major morbidity, readmissions, and reinterventions also showed considerable reduction (odds ratios of 0.64, 0.69, and 0.70, respectively). Additionally,…
A cohort study identified specific bile microRNAs (miRNAs) that differentiate malignant from benign pancreaticobiliary diseases. Among 111 patients, 14 differentially-expressed miRNAs were identified, with bile miR-340 and miR-182 significantly validated. The study achieved an area under the curve (AUC) of 0.79, demonstrating sensitivity of 65%…
Development of a biodegradable prosthesis utilizing electrospun poly(d,l-lactide-co-glycolide)-polycaprolactone-gelatin nanofibers successfully demonstrated mechanical strength, biocompatibility, and biodegradability in a pig model. This innovative scaffold maintained bile duct permeability and facilitated cell adhesion and growth without adversely affecting liver function over two years. Notably, immunohistochemical evaluations confirmed…
