Newsletter
Best Papers in General Surgery
The five that matter, every day.
The ISGPS developed a complexity and experience grading system for minimally-invasive pancreatoduodenectomy (MIPD), aimed at enhancing patient selection. This system categorizes patient risk factors and surgeon experience, enabling optimal decision-making for safe MIPD implementation. It assesses anatomical and conditional risks alongside surgeon experience and center…
A systematic review and meta-analysis analyzing 94,833 patients revealed that alvimopan significantly lowers the risk of postoperative ileus (odds ratio: 0.57) and shortens hospital stays in individuals undergoing bowel resection. These findings strongly support the routine incorporation of alvimopan into enhanced recovery after surgery programs…
A new lasso-logistic regression model was developed and validated, identifying nine independent risk factors for postpancreatectomy hemorrhage among 9,631 patients across two cohorts. The model demonstrated strong predictive accuracy, achieving an area under the receiver operating characteristic curve of 0.87 during external validation, significantly outperforming…
In a study of 282 patients with borderline resectable pancreatic cancer, those undergoing neoadjuvant treatment (NAT) followed by surgery exhibited the best overall survival (OS) of 35 months compared to 23 months for upfront surgery and 16 months for chemotherapy only. Patients receiving at least…
In patients with stage IIA rectal cancer above the peritoneal reflection who did not receive preoperative chemoradiotherapy, adjuvant chemotherapy (AC) demonstrated significantly improved 5-year overall survival (93.2% vs. 84.6%, p = .001) and recurrence-free survival (81.6% vs. 64.1%, p = .01). Patients with one or…
A study of 891 Chinese patients revealed distinct risk factors for lymph node metastasis (LNM) and prognosis in submucosal early gastric cardiac (SEGCC) versus noncardiac (SEGNCC) carcinomas. Elderly patients and specific tumor characteristics were more prevalent in SEGCC, which correlated with poorer prognoses. Univariate and…
The study established and validated task-specific metrics for assessing performance in perineal proctectomy, a complex surgical procedure. In three phases, 23 expert colorectal surgeons reached consensus on the metrics, and a subsequent assessment of 22 participants indicated a strong correlation between global and task-specific scores…
A cohort study found that minimally invasive left colectomy using total intracorporeal anastomosis (TIA) resulted in fewer intraoperative complications and comparable postoperative morbidity compared to extracorporeal anastomosis (EA). Among 246 patients, TIA demonstrated higher C-reactive protein levels and reduced relevant anastomotic bleeding but similar anastomotic…
Evidence from a multi-institutional cohort study indicates that adjuvant therapy significantly improves overall survival rates in patients with high-risk periampullary adenocarcinomas. Among 736 patients analyzed, those receiving adjuvant therapy had a median overall survival of 68.7 months compared to 61.1 months for those under observation,…
Between 1990 and 2021, the global burden of appendicitis displayed a significant decline in mortality and disability-adjusted life-years (DALYs), yet regional disparities in incidence and mortality persist. In 2021, global age-standardized mortality was 0.358 per 100,000, with the highest incidence rates in high-income Asia Pacific.…
