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General Surgery

Best Papers in General Surgery

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BMC Surg13 Jul 2024

Novel Biomarkers for Predicting Acute Mesenteric Ischaemia

A prospective multicentre study aims to identify biomarker combinations that can accurately diagnose acute mesenteric ischaemia (AMI) and distinguish between reversible and irreversible bowel ischaemia. Serum biomarkers including I-FABP, Alpha-GST, IL-6, PCT, IMA, D-lactate, D-dimer, SCUBE-1, and LBP will be measured in adult patients with…

Perspectives, Opinions and Curiosities13 Jul 2024

Nursing Care Interventions Reduce Pain and Anxiety in Ambulatory Surgery Patients

Nursing care interventions significantly reduce pain and anxiety in patients undergoing ambulatory surgery, according to a meta-analysis of nine studies. Pain reduction (SMD = -1.224) and anxiety reduction (SMD = -1.53) were substantial, though improvements in functional status were not significant. High heterogeneity was observed…

HPB & Spleen13 Jul 2024

Minimally Invasive Liver Surgery Outperforms Open Surgery in Surgical Outcomes

Minimally invasive liver resection (MILR) demonstrated superior outcomes compared to open surgery in a study of 260 patients. MILR, performed in 68% of cases, resulted in shorter operative times, less blood loss, lower rates of major complications and bile leaks, and reduced hospital stays. Despite…

Upper Gastrointestinal Tract13 Jul 2024

Malnutrition and Nutritional Support After Gastrectomy in Gastric Cancer Patients

Malnutrition, common among gastric cancer patients, can be improved with nutritional support after gastrectomy. Total gastrectomy poses significant challenges, but function-preserving surgeries show promise. Effective nutritional screening and support enhance outcomes, including reduced complications and improved quality of life. Preoperative interventions vary in effectiveness, while…

Ann Surg Oncol12 Jul 2024

Subgrading of G2 Pancreatic Neuroendocrine Tumors Reveals Behaviorally Distinct Subsets

Subgrading G2 pancreatic neuroendocrine tumors into 2A (Ki67 3% to < 10%) and 2B (10% to ≤ 20%) identifies distinct subsets with different metastasis rates and aggressiveness. G2B cases show significantly higher rates of liver/distant metastasis, lymph node metastasis, and histopathologic signs of aggressiveness compared…

Ann Surg Oncol12 Jul 2024

Circulating Exosomal MicroRNA Panel Predicts Peritoneal Metastasis in Advanced Gastric Cancer

A circulating exosomal microRNA panel, robustly predicting peritoneal metastasis in advanced gastric cancer patients, was developed and validated with remarkable accuracy. The risk-stratification model, combined with currently used tumor markers, significantly outperformed conventional clinical factors in predicting metastasis. This novel liquid biopsy assay shows potential…

Ann Gastroenterol Surg12 Jul 2024

Laparoscopic segmentectomy using ICG fluorescent navigation shows superior outcomes

Laparoscopic segmentectomy using ICG fluorescence navigation with the negative staining method showed superior outcomes compared to open segmentectomy. Patients who underwent laparoscopic surgery experienced shorter operative times, reduced blood loss, and shorter hospital stays. Additionally, they had significantly fewer grade II and grade III or…