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Best Papers in General Surgery
The five that matter, every day.
Robot-assisted oesophagectomy shows superior effectiveness in removing crucial lymph nodes near the recurrent laryngeal nerve, compared to video-assisted techniques, resulting in lower rates of nerve injury. In a multicentre trial in Asia, robot-assisted surgery successfully dissected lymph nodes in 88.3% of cases, significantly outperforming video-assisted…
Propensity score-matching analysis of 778 patients showed that additional gastrectomy after endoscopic submucosal dissection (ESD) for early gastric cancer did not significantly impact overall or disease-free survival rates compared to surgery alone. Postoperative complication rates were similar between groups. The findings suggest that additional gastrectomy…
Scissor-type knives, clutch cutter (CC) and SB knife Jr2 (SB), demonstrated comparable efficacy in colorectal endoscopic submucosal dissection. Both groups exhibited high en bloc resection rates and low complication rates, with CC showing significantly less perioperative bleeding than SB. Risk factors for prolonged procedure time…
Neoadjuvant chemoradiotherapy followed by total mesorectal excision resulted in a 3-year overall survival rate of 84% for patients with T4 and/or N2 rectal adenocarcinoma. Achieving R0 resection improved recurrence and survival rates, with T4 disease showing worse outcomes than N2. Adjuvant chemotherapy was associated with…
Identification of potential mRNA vaccine targets in pancreatic cancer patients using immune- and oxidative stress-related genes. A model incorporating ERAP2, MET, CXCL9, and AGT genes predicts patient prognosis more accurately than current models. ERAP2 aids immune activation and cancer immune evasion, MET regulates cancer cell…
A systematic review of 47 studies involving 3D liver reconstruction highlights its benefits in liver surgery. 87.2% of studies used 3D reconstructions for preoperative planning, particularly for complex hepatectomies and liver grafts. The approach improved navigation and accuracy in 55.3% of cases, facilitated graft selection…
A new classification system for extrahepatic choledochal cyst (ecc) has been established through imaging clustering, unveiling types A, B, C, and D. Significant differences in comorbidities and postoperative complications were found among the types. Factors like age, BMI, and stone presence impacted operative time. Machine…
A dedicated Oncology Nurse Navigator significantly reduced diagnostic and treatment delays, resulting in quicker access to care for cancer patients. Patients in the study group experienced shorter wait times for diagnostic testing, multi-disciplinary team discussions, oncology visits, and surgery scheduling compared to the control group.…
The study explores the role of Augmenter of Liver Regeneration (ALR) in blunt liver trauma using a rat model. ALR levels in plasma and liver tissue showed significant fluctuations depending on the time post-trauma. Plasma ALR levels peaked at 30 minutes, while intact liver tissue…
Simulation-based curriculum significantly improves surgical residents' ability to perform vascular anastomoses, as evidenced by high satisfaction ratings and improved technical skills. This six-part curriculum provides a valuable opportunity for residents to acquire critical open vascular surgical skills in an era dominated by endovascular surgery, filling…
